Analyzing the molecular structure of tubal cilia in women with and without ectopic pregnancy
Analysis of the Molecular Composition of Tubal Cilia in Patients With or Without Ectopic Pregnancy
This study is trying to see if there are differences in the tiny hair-like structures in the fallopian tubes of women with and without ectopic pregnancies to better understand fertility issues.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Centre Hospitalier Intercommunal Creteil Academic / other |
| Locations | 1 site (Créteil, Val-deMarne) |
| Trial ID | NCT05374720 on ClinicalTrials.gov |
What this trial studies
This study investigates the molecular and morphological composition of tubal cilia in women, particularly focusing on those with Primary Ciliary Dyskinesia (DCP) and those without. It aims to identify ciliary abnormalities that may be associated with ectopic pregnancies and other fertility disorders. The research involves patients scheduled for salpingectomy or hysterectomy, allowing for the collection of cilia samples for analysis. The findings could provide insights into the role of cilia in reproductive health and fertility issues.
Who should consider this trial
Good fit: Ideal candidates for this study are women over 18 years old who are scheduled for salpingectomy or hysterectomy due to conditions like ectopic pregnancy or adenomyosis.
Not a fit: Patients who are not willing to participate in the study or those under 18 years old will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of ciliary function in reproductive health, potentially leading to improved treatments for women experiencing ectopic pregnancies and fertility disorders.
How similar studies have performed: While there is limited data on the structure and function of tubal cilia in women, similar studies on ciliary function in other contexts have shown promise, indicating potential for success in this novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with scheduled salpingectomy (Ectopic pregnancy, hysterectomy for prolapsus, adenomyosis or myomectomy) * Major patients ( \>18 years) Exclusion Criteria: * Patient not willing to participate in the study
Where this trial is running
Créteil, Val-deMarne
- Centre Hospitalier Intercommunal Créteil — Créteil, Val-deMarne, France (Recruiting)
Study contacts
- Principal investigator: Rana i MITRI-FRANGIEH — Centre Hospitalier Intercommunal Créteil
- Study coordinator: Rana MITRI- FRANGIEH
- Email: rana.mitri-frangieh@chicreteil.fr
- Phone: +33 01 57 02 22 86
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.