Analyzing kidney injury risks during controlled low blood pressure anesthesia in jaw surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project investigates the effects of intentional hypotensive management using nitroglycerin during general anesthesia in patients undergoing orthognathic surgery. The study involves monitoring blood biochemical and urine parameters throughout the surgical procedure to assess renal function and identify early risk factors for acute kidney injury (AKI). By recognizing these factors early, the research aims to implement intervention strategies that could prevent postoperative AKI, contributing to Enhanced Recovery After Surgery (ERAS) goals for improved patient recovery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* America society anesthesiologist classification class I to II patients undergoing oro-maxillo-facial surgery
* unlimited mouth opening

Exclusion Criteria:

* patients with arthritis with limited mouth opening
* persistent liver dysfunction
* chronic renal insufficiency
* body mass index ≧35 kg/m2.
* past history of malignant hyperthermia or personal or family history
* diabetes with insulin treatment
* essential hypertension without controlled

Where it's running

• Kaohsiung Medical University Chung-Ho Memorial Hospital
  Kaohsiung City, Sanmin Dist, Taiwan Recruiting

Study contacts

• Principal investigator: Kuang-I Cheng, Phd — Kaohsiung Medical University Chung-Ho Memorial Hospital
• Study coordinator: Kuang-I Cheng, Phd
• Email: kuaich@gmail.com
• Phone: 886-7-3121101

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.