Analyzing hearing functions in patients with Multiple Sclerosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the auditory functions of patients diagnosed with Multiple Sclerosis by employing various auditory tests, including pure tone auditory tests, speech perception tests, and Auditory Brain Response (ABR) assessments. Additionally, cerebrospinal fluid (CSF) will be collected through lumbar puncture to analyze inflammatory markers. The study aims to correlate the results of Distortion Product Otoacoustic Emissions (DPOAE) and CSF findings to identify any statistically significant relationships. The research will involve a comprehensive selection process, including medical records review, MRI scans, and auditory assessments.

Why it matters

Who can join: the full rules

Inclusion Criteria

* age \>18 and \<50,
* no history of hearing loss,
* no psychiatric condition
* no familial history of otosclerosis/deafness/genetic hearing loss
* patients with PD and/or MS.

Exclusion Criteria

* Conductive hearing loss
* stroke \< 2 years
* cardiovascular disease non under control
* diabetes
* hypotensive disorders
* alcohol abuse
* recreational drug consumption
* epilepsy

Where it's running

• Arianna Di Stadio
  Catania, Sicily, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.