Analyzing gut bacteria in pancreatic diseases
Official title: Microbial Diversity of Pancreatic Diseases
Run by Ruijin Hospital · NCT03809247 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study looks at the gut bacteria in people with pancreatic cancer, other pancreatic diseases, and healthy individuals to see how they differ and if they can help us understand these conditions better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 3 Years to 85 Years |
| Sex | All |
| Enrollment | 330 (estimated) |
| Sponsor | Ruijin Hospital Academic / other |
| Locations | 1 site (Shanghai, Shanghai) |
| Trial ID | NCT03809247 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 3 to 85 years with confirmed pancreatic cancer or other pancreatic diseases who are eligible for surgery or ERCP.
✕Probably not a fit
Patients with serious cardiovascular disease, active infections, or a history of other cancers may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to analyze the digestive flora structure in patients with pancreatic cancer compared to those with other pancreatic diseases and healthy individuals. Participants will provide samples such as stool, blood, and digestive secretions, with additional tissue samples collected from those undergoing surgery. The goal is to identify differences in microbial communities among these groups and to uncover potential biomarkers and pathogenic mechanisms related to pancreatic diseases.
Why it matters
Potential benefit: If successful, this study could lead to the identification of new biomarkers for early detection and treatment of pancreatic diseases.
How similar studies have gone: While studies on microbial diversity in relation to various diseases exist, this specific approach focusing on pancreatic diseases is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 3 years old, ≤ 85 years old; * After MDT discussion, routine surgery or ERCP can be performed, and the postoperative pathology is clear as pancreatic cancer and other pancreatic diseases; * There is no serious damage to heart, liver and kidney function; Exclusion Criteria: * Women who are breast-feeding during pregnancy and after pregnancy; * Patients with evidence of sensory or motor neuropathy; * Those who have a clear cardiovascular disease, severe associated disease or active infection, including known HIV infection; * Those who have a history of other cancers; * Those who are allergic to drugs or their excipients
Where it's running
-
Ruijin Hospital
Shanghai, Shanghai, China Recruiting
Study contacts
- Principal investigator: Wei WANG, Dr. — Ruijin Hospital
- Study coordinator: Wei WANG, Dr.
- Email: wangwei_0306@163.com
- Phone: +86-13761648121
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.