Analyzing EEG Changes During Surgery to Measure Pain Response

Quantitative Analysis of EEG Changes in Response to Nociception

Observational Gangnam Severance Hospital · NCT06342570

This study is trying to see how brain activity changes during and after laparoscopic surgery to better understand pain responses in patients under general anesthesia.

Quick facts

Study typeObservational
Enrollment109 (estimated)
Ages19 Years and up
SexAll
SponsorGangnam Severance Hospital Academic / other
Locations1 site (Seoul)
Trial IDNCT06342570 on ClinicalTrials.gov

What this trial studies

This observational study aims to quantify nociception in patients undergoing laparoscopic surgery by using the Analgesia Nociception Index (ANI) during general anesthesia. It will analyze the differences in electroencephalogram (EEG) readings based on the level of nociception experienced by patients. Additionally, the study will continue to assess nociception during the recovery phase and correlate EEG changes with nociception levels. The goal is to enhance understanding of pain responses in surgical settings.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 19 and older who are scheduled for laparoscopic surgery.

Not a fit: Patients with certain heart conditions, central nervous system diseases, or those on specific medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies during and after laparoscopic surgeries.

How similar studies have performed: While the approach of using EEG to measure nociception is not widely established, similar studies have shown promising results in understanding pain responses.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

• Patients aged ≥ 19 undergoing laparoscopic surgery

Exclusion Criteria:

* Patients with arrhythmia
* Patients with pacemaker implantation
* Patients who have received a heart transplant
* Patients taking medications that may affect ANI (antimuscarinics, alpha-agonist, beta blockers, etc.)
* Patients with central nervous system disease (dementia, stroke, epilepsy, brain tumor, psychiatric disease, etc.)
* Patients who cannot understand the consent form

Where this trial is running

Seoul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Patients Undergoing Laparoscopic Surgery
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.