Analyzing blood samples to understand Hodgkin lymphoma prognosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on analyzing circulating tumor DNA (ctDNA) in patients with classical Hodgkin lymphoma (cHL) to identify specific somatic mutations. Blood samples will be collected at various treatment stages, including diagnosis and after chemotherapy, to correlate these mutations with treatment responses and tumor mass. Additionally, the study will assess the presence of Epstein-Barr virus (EBV) in EBV-positive patients to further understand its role in cHL prognosis. The goal is to develop a prognostic model that can guide treatment decisions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients ≥ 18 years with newly histologically confirmed classical Hodgkin lymphoma (cHL) will be enrolled
* signing the informed consent

Exclusion Criteria:

* Pacients without signing the informed consent

Where it's running

• University Hospital Hradec Kralove
  Hradec Králové, Czechia Recruiting
• University Hospital Olomouc
  Olomouc, Czechia Recruiting
• University Hospital Kralovske Vinohrady
  Prague, Czechia Recruiting
• General University Hospital
  Prague, Czechia Recruiting
• Charles University
  Prague, Czechia Active not recruiting

Study contacts

• Study coordinator: Heidi Mocikova, M.D., Ph.D.
• Email: heidi.mocikova@fnkv.cz
• Phone: +420267163554

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.