AIDE: Decision Support for Emergency Surgery in Complicated Diverticulitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study is multicenter and non-interventional, focusing on patients needing urgent surgery for complicated diverticulitis. It gathers standardized clinical, radiological, intraoperative, and surgeon-reported data, including images when available. The goal is to validate and refine an expert-informed AI-based decision-support tool without changing usual care. Data will inform future development of AI tools to assist intraoperative decision-making in emergency colorectal surgery. No experimental treatments are administered as part of the study.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Diagnosis of acute complicated diverticulitis requiring non-elective operative management
* Emergency or urgent surgery for complicated diverticulitis, including surgery after failure of non-operative management
* Minimally invasive approach: laparoscopic/robotic surgery
* Patients undergoing sigmoid resection with primary anastomosis, Hartmann's procedure, or other operative strategy according to local practice
* Availability of clinical and operative data
* Local ethical approval, authorization, or waiver according to national and institutional regulations

Exclusion Criteria:

* Age younger than 18 years
* Elective surgery for diverticular disease
* Uncomplicated diverticulitis managed non-operatively
* Surgery performed for conditions not related to diverticulitis
* Surgical procedures performed via primary open approach (i.e., no attempt at minimally invasive surgery), unless converted intraoperatively.
* Lack of required consent or authorization for data use, when required by local regulations

Where it's running

• IRCCS San Raffaele Roma
  Roma, Rm, Italy Recruiting
• eCampus university
  Novedrate, Como, Italy Enrolling by invitation

Study contacts

• Study coordinator: Belinda De Simone, MD
• Email: ariesproject2023@gmail.com
• Phone: +33665787872

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Comparing non-operative management of acute diverticulitis in medical vs surgical wards

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  Recruiting Ospedali Riuniti Trieste · Trieste, TS · NCT06265649

• Evaluating surgical options for treating peritonitis from perforated diverticulitis

  This study is testing two different surgical methods for treating peritonitis caused by perforated diverticulitis to see which one helps patients recover better.

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• Comparing vacuum assisted closure and on-demand relaparotomy for fecal peritonitis

  This study is testing whether using vacuum assisted closure or doing surgery as needed is better for patients with fecal peritonitis in terms of recovery and complications.

  Recruiting Odense University Hospital · Odense, Fyn · NCT03932461

• International registry for emergency surgery and trauma

  This study is setting up a worldwide registry for emergency surgeries and trauma cases to help doctors track their results and find better ways to treat patients.

  Recruiting A.O. Ospedale Papa Giovanni XXIII · Pisa · NCT03643718

• Personalized treatment with Pentaglobin® for patients with peritonitis after surgery

  This study is testing if adding Pentaglobin® to standard care can help patients recover better from peritonitis after surgery.

  Recruiting at 12 sites Phase 2 RWTH Aachen University · Vienna and 19 other locations · NCT03334006

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.