Comparing non-operative management of acute diverticulitis in medical vs surgical wards

Acute Left Colon Diverticulitis: is it Still a Surgical Disease When Only Medical Treatment is Required? A Retrospective Study Based on Propensity Score Matching

Observational Ospedali Riuniti Trieste · NCT06265649

This study looks at how well non-surgical treatment for acute diverticulitis works for patients in medical versus surgical hospital wards.

Quick facts

Study typeObservational
Enrollment175 (estimated)
Ages18 Years and up
SexAll
SponsorOspedali Riuniti Trieste Academic / other
Locations1 site (Trieste, TS)
Trial IDNCT06265649 on ClinicalTrials.gov

What this trial studies

This observational study examines the outcomes of non-operative management (NOM) for acute left colon diverticulitis (ALCD) in both surgical and non-surgical hospital wards. It aims to assess clinical outcomes, length of hospitalization, and follow-up care for patients treated with NOM. The study is motivated by the rising prevalence of ALCD and the need to optimize healthcare resources by avoiding unnecessary surgical admissions. By analyzing data from patients diagnosed with ALCD through contrast-enhanced CT scans, the study seeks to provide insights into the effectiveness of NOM in different hospital settings.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with uncomplicated acute left colon diverticulitis who are undergoing non-operative management.

Not a fit: Patients with complicated diverticulitis requiring immediate surgical intervention will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more efficient management of acute diverticulitis, reducing unnecessary surgical interventions and hospital stays.

How similar studies have performed: While there is limited data on similar comparisons, the study addresses a growing need for optimized management of diverticulitis, suggesting a novel approach to patient care.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients affected by ALCD using a contrast-enhanced CT scan at admission undergoing NOM

Exclusion Criteria:

* immediate indication for surgery (i.e. patients with Hinchey III or IV ALCD or septic patients with Hinchey II)

Where this trial is running

Trieste, TS

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions DiverticulitisColon DiseaseAcute Diverticulitisdiverticulitisnon-operative management
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.