Clinical trial Recruiting at 1 site Observational Ages 18 and up

Comparing non-operative management of acute diverticulitis in medical vs surgical wards

Official title: Acute Left Colon Diverticulitis: is it Still a Surgical Disease When Only Medical Treatment is Required? A Retrospective Study Based on Propensity Score Matching

Run by Ospedali Riuniti Trieste · NCT06265649 · Data updated 2026-11-12

This study looks at how well non-surgical treatment for acute diverticulitis works for patients in medical versus surgical hospital wards.

More Diverticulitis trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment175 (estimated)
SponsorOspedali Riuniti Trieste
Academic / other
Locations1 site (Trieste, TS)
StatusRecruiting
StartedJanuary 1, 2024
Main results expectedDecember 2025
Study endsJanuary 2026
Registry record updatedApril 4, 2025
Trial IDNCT06265649 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with uncomplicated acute left colon diverticulitis who are undergoing non-operative management.

Probably not a fit

Patients with complicated diverticulitis requiring immediate surgical intervention will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines the outcomes of non-operative management (NOM) for acute left colon diverticulitis (ALCD) in both surgical and non-surgical hospital wards. It aims to assess clinical outcomes, length of hospitalization, and follow-up care for patients treated with NOM. The study is motivated by the rising prevalence of ALCD and the need to optimize healthcare resources by avoiding unnecessary surgical admissions. By analyzing data from patients diagnosed with ALCD through contrast-enhanced CT scans, the study seeks to provide insights into the effectiveness of NOM in different hospital settings.

Why it matters

Potential benefit: If successful, this study could lead to more efficient management of acute diverticulitis, reducing unnecessary surgical interventions and hospital stays.

How similar studies have gone: While there is limited data on similar comparisons, the study addresses a growing need for optimized management of diverticulitis, suggesting a novel approach to patient care.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients affected by ALCD using a contrast-enhanced CT scan at admission undergoing NOM

Exclusion Criteria:

* immediate indication for surgery (i.e. patients with Hinchey III or IV ALCD or septic patients with Hinchey II)

Where it's running

  • Manuela Mastronardi
    Trieste, Ts, Italy
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.