AI-based cognitive training for people after stroke

Effect of Artificial Intelligence-Based Training on Cognitive Functions in Patients With Stroke

Not applicable Interventional Cairo University · NCT07452276

This trial will test whether an AI-based mobile app can help adults aged 45–60 improve thinking and memory after a stroke.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages45 Years to 60 Years
SexAll
SponsorCairo University Academic / other
Locations1 site (Cairo, Egypt)
Trial IDNCT07452276 on ClinicalTrials.gov

What this trial studies

This interventional study enrolls adults 45–60 years old with chronic stroke (at least 3 months post-onset) and cognitive impairment (MoCA ≤ 26). Participants will receive either Cognifit, an AI-powered mobile cognitive training application, or conventional cognitive rehabilitation. Cognitive function will be measured before and after the intervention to compare changes between the two groups. The study is conducted at the Physical Therapy department of Cairo University in Cairo, Egypt.

Who should consider this trial

Good fit: Adults aged 45–60 in the chronic stage of stroke (≥3 months) with cognitive impairment (MoCA ≤ 26), who are medically stable and able to follow instructions, are ideal candidates.

Not a fit: People with severe visual, hearing, or speech impairments, other neurological or psychiatric disorders, unstable systemic disease, or severe depression (BDI > 29) are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, the app could offer an accessible way to improve memory, attention, and other thinking skills for people recovering from stroke.

How similar studies have performed: Previous research on computer- and app-based cognitive training after stroke has shown mixed but sometimes positive results, while AI-specific app evidence remains limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient's age will range from 45- 60 years.

  * Diagnosis of stroke in the chronic stage (≥3 months post-onset).
  * Presence of cognitive impairment confirmed by a Montreal Cognitive Assessment (MoCA) score ≤ 26.
  * Medically stable and able to follow instructions.
  * patients with memory deficits following stroke

Exclusion Criteria:

\- Patients will be excluded if they have:

* Severe visual, hearing, or speech impairments prevent participation.
* History of other neurological or psychiatric disorders.
* Unstable cardiovascular or systemic disease.
* Severe depression (Beck Depression Inventory \> 29).

Where this trial is running

Cairo, Egypt

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post-Stroke Cognitive ImpairmentStrokeArtifical Intelligence
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.