Clinical trial Recruiting at 1 site Interventional Ages 45 to 60

AI-based cognitive training for people after stroke

Official title: Effect of Artificial Intelligence-Based Training on Cognitive Functions in Patients With Stroke

Run by Cairo University · NCT07452276 · Data updated 2026-11-12

This trial will test whether an AI-based mobile app can help adults aged 45–60 improve thinking and memory after a stroke.

Quick facts

Study typeInterventional
Ages45 Years to 60 Years
SexAll
Enrollment40 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Cairo, Egypt)
StatusRecruiting
StartedJanuary 1, 2026
Main results expectedFebruary 1, 2026
Study endsJune 6, 2026
Registry record updatedMarch 5, 2026
Trial IDNCT07452276 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 45–60 in the chronic stage of stroke (≥3 months) with cognitive impairment (MoCA ≤ 26), who are medically stable and able to follow instructions, are ideal candidates.

Probably not a fit

People with severe visual, hearing, or speech impairments, other neurological or psychiatric disorders, unstable systemic disease, or severe depression (BDI > 29) are unlikely to benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study enrolls adults 45–60 years old with chronic stroke (at least 3 months post-onset) and cognitive impairment (MoCA ≤ 26). Participants will receive either Cognifit, an AI-powered mobile cognitive training application, or conventional cognitive rehabilitation. Cognitive function will be measured before and after the intervention to compare changes between the two groups. The study is conducted at the Physical Therapy department of Cairo University in Cairo, Egypt.

Why it matters

Potential benefit: If successful, the app could offer an accessible way to improve memory, attention, and other thinking skills for people recovering from stroke.

How similar studies have gone: Previous research on computer- and app-based cognitive training after stroke has shown mixed but sometimes positive results, while AI-specific app evidence remains limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient's age will range from 45- 60 years.

  * Diagnosis of stroke in the chronic stage (≥3 months post-onset).
  * Presence of cognitive impairment confirmed by a Montreal Cognitive Assessment (MoCA) score ≤ 26.
  * Medically stable and able to follow instructions.
  * patients with memory deficits following stroke

Exclusion Criteria:

\- Patients will be excluded if they have:

* Severe visual, hearing, or speech impairments prevent participation.
* History of other neurological or psychiatric disorders.
* Unstable cardiovascular or systemic disease.
* Severe depression (Beck Depression Inventory \> 29).

Where it's running

  • Physical therapy- Cairo University
    Cairo, Egypt, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.