Clinical trial Recruiting at 1 site Observational Ages 18 and up

AI-assisted gender prediction from the jawbone using CBCT measurements

Official title: The Accuracy of Artificial Intelligence in Gender Prediction Using Morphometric Analysis of the Mandible - a Validity Study

Run by Cairo University · NCT07726290 · Data updated 2026-11-12

A retrospective study tests whether AI can predict a person’s gender from measurements of the mandible taken from existing CBCT scans.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment385 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedJune 1, 2026
Main results expectedMarch 30, 2027
Study endsMay 1, 2027
Registry record updatedJuly 24, 2026
Trial IDNCT07726290 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (age 18 and older) whose CBCT scans clearly image the mandible and meet quality criteria.

Probably not a fit

Scans with significant artifacts, congenital anomalies, large pathologies, or mandible trauma may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study uses pre-existing CBCT scans from adult Egyptian patients to create a deep learning model that automatically identifies anatomical points, takes specified mandibular measurements, and predicts gender. The model’s performance will be compared against the known gender in patient records, and its ability to match radiologist measurements will be evaluated. The primary goal is to measure accuracy, precision, and recall of the AI in gender determination, with a secondary aim to assess the AI’s accuracy in anatomical point placement and measurements. The study leverages automated mandibular segmentation and three-dimensional neural networks to test whether AI can assist forensic odontology workflows.

Why it matters

Potential benefit: If successful, AI-assisted morphometric analysis could speed up and standardize gender determination in forensic cases.

How similar studies have gone: Previous work in similar AI-forensic applications has shown promise, but this exact approach using CBCT mandibular measurements is novel in this setting.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Scans belonging to patients above or at the age of 18 years (≥ 18 years)
* Scans that image the area of interest clearly (mandible) with a craniofacial or maxillomandibular field of view.
* Good quality of the scan with no artefacts

Exclusion Criteria:

* CBCT scans with significant artifacts (e.g. metal artefact) affecting visualization of the mandible
* Congenital craniofacial anomalies affecting the mandibular anatomy
* Large pathologies that affect the mandible's dimensions and cause significant bone loss.
* Trauma to the mandible

Where it's running

  • Faculty of Dentistry, Cairo University
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.