AI-assisted decision-making for ocular diseases

A Study on Ophthalmic Multimodal AI-Assisted Medical Decision-Making Based on Imaging and Electronic Medical Record Data

Observational The Eye Hospital of Wenzhou Medical University · NCT06755190

This study is testing if an AI tool can help eye doctors make better decisions and improve treatment for patients with eye diseases by using different types of health data.

Quick facts

Study typeObservational
Enrollment5000000 (estimated)
SexAll
SponsorThe Eye Hospital of Wenzhou Medical University Academic / other
Locations5 sites (Zhuhai, Guangdong and 4 other locations)
Trial IDNCT06755190 on ClinicalTrials.gov

What this trial studies

This observational study evaluates the effectiveness of an AI-assisted medical decision support system in ophthalmology by integrating multimodal data from various sources, including imaging and electronic health records. The aim is to enhance diagnostic accuracy and streamline clinical workflows for ocular diseases. By leveraging deep learning techniques, the study seeks to provide personalized treatment options and improve patient outcomes. The research involves multiple centers and focuses on patients with confirmed ocular diseases who have comprehensive health records.

Who should consider this trial

Good fit: Ideal candidates include patients with confirmed diagnoses of ocular diseases who have received treatment at participating hospitals and have comprehensive electronic health records.

Not a fit: Patients without a confirmed diagnosis of ocular diseases or those lacking sufficient follow-up records may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve the early detection and treatment of ocular diseases, leading to better vision outcomes for patients.

How similar studies have performed: Other studies utilizing AI in medical decision-making have shown promising results, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1.All patients who have received treatment at multiple centers, including The Eye Hospital of Wenzhou Medical University, First Affiliated Hospital of Wenzhou Medical University, Second Affiliated Hospital of Wenzhou Medical University, ZhuHai Hospital, and Macau University of Science and Technology Hospital.

2.Availability of comprehensive electronic health records (EHR), including: Ophthalmic images (e.g., fundus photography, OCT, or slit-lamp images). Electronic medical records (e.g., diagnosis, treatment, and follow-up notes). Examination results (e.g., visual acuity, intraocular pressure, or laboratory tests). 3.Patients with a clear and confirmed diagnosis of one or more ocular diseases. 4.Patients with sufficient follow-up records to allow assessment of disease progression or prognosis, if applicable.

1. All ophthalmology patients who have previously received treatment at the Department of Ophthalmology, the Eye Hospital of Wenzhou Medical University, First Affiliated Hospital of Wenzhou Medical University, Second Affiliated Hospital of Wenzhou Medical University, Zhuhai People's Hospital, and the University Hospital.
2. Availability of comprehensive electronic health records (EHR), including: Ophthalmic images (e.g., fundus photography, OCT, or slit-lamp images). Electronic medical records (e.g., diagnosis, treatment, and follow-up notes). Examination results (e.g., visual acuity, intraocular pressure, or laboratory tests).
3. Patients with a clear and confirmed diagnosis of one or more ocular diseases.
4. Patients with sufficient follow-up records to allow assessment of disease progression or prognosis, if applicable.

Exclusion Criteria:

1. Incomplete or missing critical EHR components.
2. Cases with ambiguous or unverified diagnoses that cannot be clearly categorized.
3. Duplicated or redundant data from the same patient.

Where this trial is running

Zhuhai, Guangdong and 4 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ocular Diseasesocular diseasesOphthalmic Multimodal AI-Assisted Medical Decision-MakingArtificial Intelligence
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.