Aerobic fitness and balance in people with multiple sclerosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study compares MS patients with high versus low aerobic fitness to see how it relates to walking speed, balance, sensory dual-task performance, balance confidence, and fatigue. Researchers will group participants based on the 6-minute walk test and then collect data during a joint clinical and dual-task protocol using standardized tests for mobility, balance, sensation, confidence, and fatigue. The study is conducted at Süleyman Demirel University Hospital in Isparta, with informed consent obtained from all participants. Eligible participants include adults with relapsing-remitting or progressive MS, and certain health and cognitive criteria are required. The aim is to better understand how aerobic fitness relates to functional performance in MS and whether higher fitness associates with improved outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Having been diagnosed with Relapsing-Remitting or Progressive MS.
* Being between 18-65 years of age.
* Having an Expanded Disability Status Scale score between 1.5-5.
* Being able to walk independently or with a unilateral assistive device.
* Having full cooperation and orientation, and a cognitive level to understand given commands: Mini Mental Test score of 24 or higher.

Exclusion Criteria:

* Having experienced an MS relapse or received acute corticosteroid treatment within the last 3 months.
* Having an additional neurological, orthopedic, or rheumatological condition unrelated to MS that may affect balance and walking.
* Having severe cardiovascular or respiratory disease that may make aerobic fitness assessment risky.
* Having significant vision or hearing loss that would impede understanding test instructions.
* Experiencing significant pain during measurements.
* Having cognitive impairment that would prevent understanding or answering questions - scoring below 24 on the Minimental Test.

Where it's running

• Süleyman Demirel Üniversitesi Araştırma ve Uygulama Hastanesi
  Isparta, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: ALEYNA OZDAMAR YUCEL, MSc
• Email: aleynayucel@sdu.edu.tr
• Phone: +90 507 950 74 57

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.