Aerobic exercise program for adults on hemodialysis
Impact of Aerobic Exercises on Serum Uric Acid Levels in Hemodialysis Patients
This will test whether adding a six-week aerobic exercise program to usual physical therapy lowers uric acid, increases walking distance, and improves quality of life for adults aged 40–60 on hemodialysis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 32 (estimated) |
| Ages | 40 Years to 60 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT07076888 on ClinicalTrials.gov |
What this trial studies
This randomized controlled trial will enroll 32 hemodialysis patients aged 40–60 and randomly assign them to a combined conventional physical therapy plus aerobic exercise group or to conventional physical therapy alone. The aerobic program lasts six weeks with three sessions per week of 20–45 minutes each, delivered at the Physical Therapy Faculty, Cairo University. Outcomes measured before and after the intervention include serum uric acid (mg/dL), functional capacity via the Six-Minute Walk Test, and health-related quality of life using the KDQOL-SF™ Arabic version. Participants must be medically stable on hemodialysis for at least three months and able to follow commands and perform exercise.
Who should consider this trial
Good fit: Adults aged 40–60 who have been on stable hemodialysis for at least three months, are medically stable, able to follow commands, and can participate in exercise are ideal candidates.
Not a fit: Patients with significant cardiovascular or respiratory disease, severe cognitive or psychiatric impairment, acute medical conditions, or an inability to exercise are unlikely to benefit or be eligible for this program.
Why it matters
Potential benefit: If successful, the program could lower serum uric acid and meaningfully improve walking endurance and quality of life for people on hemodialysis.
How similar studies have performed: Exercise programs have improved cardiovascular fitness and quality of life in dialysis and non-dialysis populations and some studies have reported reduced uric acid, but evidence specifically in hemodialysis patients is limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Hemodialysis patients aged 40-60years 2. Patients are medically stable and able to participate in physical activity. 3. Participants are able to understand the commands. 4. Participants must be stable on hemodialysis for at least 3 months. Exclusion Criteria: 1. Patients with significant cardiovascular or respiratory diseases, or other conditions that could impair their ability to exercise. 2. Severe cognitive impairment or psychiatric conditions that could interfere with study participation. 3. patients with acute medical conditions.
Where this trial is running
Cairo
- Physical Therapy faculty, Cairo University — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Doaa Rafat Assistant professor of physical therapy - Cairo university
- Email: doaa.rafat@pt.cu.edu.eg
- Phone: 201005591580
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.