Adding a new pain management technique to breast cancer surgery
Contribution of Transversus Thoracis Plane Block in Combination With Serratus Anterior Plane Block to the Quality of Recovery After Breast Cancer Surgery: a Randomized Controlled Trial
NA · Bezmialem Vakif University · NCT06082141
This study is testing a new way to manage pain after breast cancer surgery by combining two techniques to see if it helps patients feel better and use less opioid medication.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | Female |
| Sponsor | Bezmialem Vakif University (other) |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT06082141 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of combining two regional analgesic techniques, the Transversus thoracis plane block and the Serratus anterior plane block, to improve postoperative pain management in patients undergoing breast cancer surgery. The goal is to reduce opioid use and enhance recovery quality by minimizing acute pain and preventing chronic pain development. The study will enroll patients scheduled for breast cancer surgery who meet specific eligibility criteria, focusing on those with a BMI between 20 and 35 and ASA physical status I-III.
Who should consider this trial
Good fit: Ideal candidates for this study are women scheduled for breast cancer surgery with a BMI between 20 and 35 and classified as ASA I-III.
Not a fit: Patients with severe comorbidities, significant opioid use, or contraindications to the study interventions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative pain and opioid consumption, leading to improved recovery outcomes for breast cancer surgery patients.
How similar studies have performed: Previous studies have shown promising results with regional analgesic techniques in breast cancer surgery, indicating that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA I-II-III * BMI 20 to 35 kg / m2 * Patients scheduled for breast cancer surgery procedure Exclusion Criteria: * Patients with previously known allergies to the drugs to be used in the study, * Infection near the puncture site, * Patients with previous symptoms of neurological disease (TIA, syncope, dementia, etc.) * Known coagulation disorders, * Alcohol and drug use, * Disorder of consciousness, * Opioid use equal to or greater than 60 mg oral morphine equivalent per day, * Patients with pre-existing neuropathic pain, * Liver failure, renal failure, cardiac failure * Morbid obesity (body mass index \[BMI\] \> 35 kg m-2) * Uncontrolled diabetes mellitus * Women during pregnancy or breastfeeding * Not approving the informed consent form
Where this trial is running
Istanbul
- Aylin Ceren Şanlı — Istanbul, Turkey (RECRUITING)
Study contacts
- Study coordinator: Aylin Ceren Sanli, Asist Dr
- Email: asanli@bezmialem.edu.tr
- Phone: +0905496522412
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Acute Pain, Opioid Use, Quality of recovery-15, Serratus anterior plan block, Transversus thoracis plan block