Adaptive school-based interventions to prevent dental caries in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

BASICS uses a SMART design to tailor preventive care for dental caries delivered in school settings, embedding dynamic treatment regimes to find the most effective sequence and intensity of interventions. The trial includes interventions such as silver diamine fluoride, glass ionomer sealants, fluoride varnishes, and hygiene support, with a focus on reducing nonresponse and optimizing resource use. Participants are children in participating schools, assessed for response to treatment and guided through adaptive pathways based on their needs. The study emphasizes addressing health disparities by testing personalized approaches in diverse populations and school environments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Be enrolled in participating schools
2. Be between the ages of 5 and 13 years
3. Provide parental/guardian informed consent
4. Child assent

Exclusion Criteria:

1. Ulcerative gingivitis or stomatitis
2. Known sensitivity to silver or other heavy-metal ions
3. More than six affected sites
4. Those who have had full mouth gingivectomies
5. Patients showing abnormal skin sensitization in daily circumstances
6. Those who have had pulp capping

Where it's running

• Smiles For Students
  Glenwood Springs, Colorado, United States Recruiting

Study contacts

• Principal investigator: Ryan R Ruff, PhD, MPH — New York University College of Dentistry/Epidemiology
• Study coordinator: Ryan R Ruff, PhD, MPH
• Email: ryan.ruff@nyu.edu
• Phone: 212-998-9663

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.