Clinical trial Recruiting at 1 site Phase 3 Interventional Ages 16 to 35 Women only

Acute Sodium Bicarbonate Supplementation in Female Basketball Players

Official title: Evaluation of the Effect of Acute Sodium Bicarbonate Supplementation on Physical Capacity and Blood Biochemical Marker Concentrations in Highly Trained Female Basketball Players

Run by Poznan University of Physical Education · NCT07730606 · Data updated 2026-11-12

This study tests whether a single dose of sodium bicarbonate helps highly trained female basketball players perform better and show different blood markers than a placebo.

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Quick facts

PhasePhase 3
Study typeInterventional
Ages16 Years to 35 Years
SexWomen only
Enrollment100 (estimated)
SponsorPoznan University of Physical Education
Academic / other
Locations1 site (Poznan)
StatusRecruiting
StartedMarch 1, 2026
Main results expectedDecember 1, 2027
Study endsDecember 1, 2027
Registry record updatedJuly 28, 2026
Trial IDNCT07730606 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy, highly trained female basketball players aged 16–35 with regular training, games, and no contraindications to SB supplementation.

Probably not a fit

Individuals who do not tolerate sodium bicarbonate well or who have contraindications may not experience performance benefits and could experience adverse effects.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, double-blind, placebo-controlled crossover trial in highly trained female basketball players. A single dose of sodium bicarbonate at 0.3 g/kg body mass is taken 90 minutes before exercise, with sessions separated by a washout period. The study compares acute SB supplementation to placebo to see effects on physical capacity and blood biochemical markers, addressing a gap in data for female athletes in team sports. The crossover design allows each participant to act as her own control, enhancing the precision of the findings. The trial aims to elucidate sex- and condition-specific responses to acute buffering strategies during repeated high-intensity efforts.

Why it matters

Potential benefit: If successful, this approach could inform targeted, gender-specific loading strategies to enhance performance in high-intensity, intermittent sports.

How similar studies have gone: Previous studies on sodium bicarbonate show mixed results and have mostly included male athletes; this study adds evidence in female, high-level basketball players.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* female sex,
* age 16 to 35 years,
* good general health condition and well-being,
* regular menstrual cycles,
* written informed consent to participate in the study before its commencement,
* at least a high level of training status,
* at least 4 years of training experience in basketball,
* participation in at least 3 basketball-specific training sessions per week,
* participation in at least 1 basketball game per week.

Exclusion Criteria:

* male sex,
* use of hormonal contraceptives,
* current injury or musculoskeletal condition limiting participation in training or competition,
* health-related or medical contraindications, including menstrual disorders, planned pregnancy, or anemia,
* use of supplements within 3 months before the study, except for regular use of protein supplements, carbohydrate supplements, or isotonic drinks,
* failure to meet the study protocol assumptions or unwillingness to follow study procedures.

Where it's running

  • Department of Sports Dietetics, Poznan University of Physical Education Poznań
    Poznan, Poland
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.