Clinical trial Recruiting at 1 site Phase2; Phase3 Interventional Ages 16 to 50 Women only

Two-week multi-strain probiotic for female national-team rowers

Official title: Effect of a Short-term Multi-strain Probiotic Supplementation on the Exercise- Associated Gastrointestinal Disturbances in Trained Female Athletes Under Controlled Conditions During Professional Training Cycle

Run by Poznan University of Physical Education · NCT07252778 · Data updated 2026-11-12

This project will test whether a 2-week multi-strain probiotic can reduce exercise-related gut symptoms and gut perturbations in high-level female rowers.

Quick facts

PhasePhase2; Phase3
Study typeInterventional
Ages16 Years to 50 Years
SexWomen only
Enrollment30 (estimated)
SponsorPoznan University of Physical Education
Academic / other
Locations1 site (Poznan, Wielkopolska)
StatusRecruiting
StartedNovember 20, 2025
Main results expectedJune 1, 2027
Study endsJune 30, 2027
Registry record updatedNovember 28, 2025
Trial IDNCT07252778 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal participants are medically cleared female rowers from the national team with at least 5 years of training experience who are available to attend the on-site training camp and are not using antibiotics or probiotic/prebiotic supplements.

Probably not a fit

People with chronic gastrointestinal disease, recent GI surgery, recent antibiotic use, current use of GI-targeting medications or supplements, males, or non-elite recreational athletes are unlikely to gain direct benefit from these specific results.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

High-level female members of the Polish national rowing team will take either a multi-strain probiotic supplement or a placebo over a strictly controlled 2-week training camp. Researchers will track exercise-associated gastrointestinal symptoms, gut barrier and inflammatory biomarkers, and microbiota measures alongside standard training and performance metrics. The protocol excludes athletes with recent antibiotic use, existing GI disease, or current probiotic/prebiotic use to reduce confounding. All procedures occur on-site at the training camp with controlled conditions for diet and exercise to isolate the supplement effect.

Why it matters

Potential benefit: If successful, the intervention could reduce GI symptoms during training, improve gut barrier function, and potentially aid recovery and performance.

How similar studies have gone: Some prior work reports strain-specific probiotic benefits on gut barrier function and symptoms in clinical and athletic contexts, but well-controlled evidence in elite female rowers is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* belonging to the national rowing team;
* training experience ≥5 years;
* a currently issued medical certificate confirming
* good health and capacity to practice sports;
* good health without chronic health disorders;
* written informed consent to participate.

Exclusion Criteria:

* injury, any health contraindication or failure to perform exercise procedures;
* gastrointestinal infections, diseases, disorders;
* past history of gastrointestinal surgery, and
* other self-reported gastrointestinal issues;
* reporting symptoms of infection or taking any medication (e.g. antibiotics) for 4 weeks before the study protocol;
* current supplementation of prebiotics,
* probiotics, synbiotics (last 4 weeks);
* current intake of pharmaceutical agents (e.g., nonsteroidal anti-inflammatory drugs, laxatives, antidiarrhea agents, antacids, and/or antiemetics) (last 4 weeks);
* failure to follow the study protocol;
* declared general feeling of being unwell;
* pregnancy or current pregnancy planning.

Where it's running

  • Department of Sports Dietetics, Poznan University of Physical Education Poznań
    Poznan, Wielkopolska, Poland
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.