Two-week multi-strain probiotic for female national-team rowers
Effect of a Short-term Multi-strain Probiotic Supplementation on the Exercise- Associated Gastrointestinal Disturbances in Trained Female Athletes Under Controlled Conditions During Professional Training Cycle
This project will test whether a 2-week multi-strain probiotic can reduce exercise-related gut symptoms and gut perturbations in high-level female rowers.
Quick facts
| Phase | Phase2; Phase3 |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 16 Years to 50 Years |
| Sex | Female |
| Sponsor | Poznan University of Physical Education Academic / other |
| Locations | 1 site (Poznan, Wielkopolska) |
| Trial ID | NCT07252778 on ClinicalTrials.gov |
What this trial studies
High-level female members of the Polish national rowing team will take either a multi-strain probiotic supplement or a placebo over a strictly controlled 2-week training camp. Researchers will track exercise-associated gastrointestinal symptoms, gut barrier and inflammatory biomarkers, and microbiota measures alongside standard training and performance metrics. The protocol excludes athletes with recent antibiotic use, existing GI disease, or current probiotic/prebiotic use to reduce confounding. All procedures occur on-site at the training camp with controlled conditions for diet and exercise to isolate the supplement effect.
Who should consider this trial
Good fit: Ideal participants are medically cleared female rowers from the national team with at least 5 years of training experience who are available to attend the on-site training camp and are not using antibiotics or probiotic/prebiotic supplements.
Not a fit: People with chronic gastrointestinal disease, recent GI surgery, recent antibiotic use, current use of GI-targeting medications or supplements, males, or non-elite recreational athletes are unlikely to gain direct benefit from these specific results.
Why it matters
Potential benefit: If successful, the intervention could reduce GI symptoms during training, improve gut barrier function, and potentially aid recovery and performance.
How similar studies have performed: Some prior work reports strain-specific probiotic benefits on gut barrier function and symptoms in clinical and athletic contexts, but well-controlled evidence in elite female rowers is limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * belonging to the national rowing team; * training experience ≥5 years; * a currently issued medical certificate confirming * good health and capacity to practice sports; * good health without chronic health disorders; * written informed consent to participate. Exclusion Criteria: * injury, any health contraindication or failure to perform exercise procedures; * gastrointestinal infections, diseases, disorders; * past history of gastrointestinal surgery, and * other self-reported gastrointestinal issues; * reporting symptoms of infection or taking any medication (e.g. antibiotics) for 4 weeks before the study protocol; * current supplementation of prebiotics, * probiotics, synbiotics (last 4 weeks); * current intake of pharmaceutical agents (e.g., nonsteroidal anti-inflammatory drugs, laxatives, antidiarrhea agents, antacids, and/or antiemetics) (last 4 weeks); * failure to follow the study protocol; * declared general feeling of being unwell; * pregnancy or current pregnancy planning.
Where this trial is running
Poznan, Wielkopolska
- Department of Sports Dietetics, Poznan University of Physical Education Poznań — Poznan, Wielkopolska, Poland (Recruiting)
Study contacts
- Study coordinator: Natalia Główka, PhD
- Email: glowka@awf.poznan.pl
- Phone: +48 691 756 944
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.