Combining beta-alanine and sodium bicarbonate to improve physical capacity and blood markers in female basketball players
Evaluation of the Synergistic Effect of β-alanine and Sodium Bicarbonate Supplementation on Physical Capacity and Blood Biochemical Markers Concentrations in Trained Female Basketball Players
PHASE3 · Poznan University of Physical Education · NCT07092930
This trial tests whether taking beta-alanine and sodium bicarbonate, alone or together, can improve performance and blood biochemical markers in highly trained female basketball players.
Quick facts
| Phase | PHASE3 |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 16 Years to 40 Years |
| Sex | Female |
| Sponsor | Poznan University of Physical Education (other) |
| Locations | 1 site (Poznan, Wielkopolska) |
| Trial ID | NCT07092930 on ClinicalTrials.gov |
What this trial studies
This randomized, double-blind, placebo-controlled, parallel-group trial uses a four-arm design (BA+SB, BA+placebo, placebo+SB, placebo+placebo) to measure chronic supplementation effects in highly trained female basketball players. Participants will follow the supplementation protocol over a multi-week period while performing standardized physical capacity tests and providing blood samples for biochemical marker analysis. The study excludes participants with injuries, health contraindications, or recent use of ergogenic supplements and requires medical clearance and a minimum training history. Outcomes will compare individual and combined effects of intracellular (beta-alanine) and extracellular (sodium bicarbonate) buffering strategies on repeated high-intensity performance and related blood markers.
Who should consider this trial
Good fit: Highly trained female basketball players in good health with medical clearance, at least four years of training experience, and a minimum of four weekly workouts in their sport.
Not a fit: Recreational athletes, males, injured athletes, those with health contraindications, or anyone who has recently used ergogenic buffering supplements are unlikely to benefit or be eligible for this protocol.
Why it matters
Potential benefit: If successful, this could provide female basketball players with an evidence-based nutritional option to improve repeated high-intensity performance and related blood markers.
How similar studies have performed: Most prior research focused on male participants and acute protocols with mixed results, so a chronic four-arm randomized trial in female team-sport athletes is effectively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * written consent to participate, * general good health condition, * a current medical clearance to practice sports, * training experience: at least 4 years, * minimum of 4 workout sessions (in the discipline covered by the study) a week. Exclusion Criteria: * current injury, * any health-related contraindication, * declared general feeling of being unwell, * taking supplements, especially ergogenic supplements that modulate extra- and intracellular capacity 3 months prior to research (except taking protein and/or carbohydrate powders, isotonic drinks), * unwilling to follow the study protocol.
Where this trial is running
Poznan, Wielkopolska
- Department of Sports Dietetics, Poznan University of Physical Education Poznań — Poznan, Wielkopolska, Poland (RECRUITING)
Study contacts
- Study coordinator: Jakub Adamczewski, MSc
- Email: adamczewski@awf.poznan.pl
- Phone: +48 66 317 56 06
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Supplementation, Sports, Female Athletes, Beta-alanine, Sodium bicarbonate, Ergogenic aids, Sports nutrition, Team sports