Clinical trial Recruiting at 1 site Observational

Acute Ischemic Stroke in People with Active Cancer

Official title: Clinical Characteristics and Stroke Recurrence in Patients With Acute Ischemic Stroke and Active Cancer: The CAT-AIS Multicenter Prospective Observational Study

Run by Osaka University · NCT07819526 · Data updated 2026-11-12

This study looks at how often people with active cancer have another ischemic stroke after an initial event, to see what factors might be linked to a recurrence.

Quick facts

Study typeObservational
SexAll
Enrollment500 (estimated)
SponsorOsaka University
Academic / other
Locations1 site (Suita, Osaka)
StatusRecruiting
StartedMarch 1, 2026
Main results expectedJune 30, 2027
Study endsMarch 31, 2032
Registry record updatedSeptember 21, 2026
Trial IDNCT07819526 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with acute ischemic stroke and active cancer at the time of the stroke who receive standard care at participating centers.

Probably not a fit

Patients whose stroke does not recur or whose outcomes are not influenced by cancer status may see no direct benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter prospective observational study conducted at 24 hospitals in Japan. It follows patients who have active cancer and recently experienced an acute ischemic stroke to observe how often another stroke happens within three months and what clinical factors may be associated with such recurrences. Data collected include cancer details, stroke characteristics, tests, treatments, and other outcomes, without assigning any specific treatment. The goal is to understand recurrence rates and related factors to inform future care decisions. No experimental interventions are performed; care remains at the discretion of the treating physicians.

Why it matters

Potential benefit: If successful, the study could clarify risk factors for recurrent stroke in cancer patients and help tailor follow-up and management to reduce future events.

How similar studies have gone: Previous observational work in cancer-associated stroke has shown variability in recurrence risk, making this study's prospective, multicenter design valuable for broader insight.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Acute ischemic stroke diagnosed within 7 days after symptom onset or the time last known well.
2. Active cancer at the time of the index stroke, as defined below.

Exclusion Criteria:

1. The patient or a legally acceptable representative indicates that the patient does not wish to participate.
2. The investigator considers enrolment inappropriate.

Where it's running

  • The Univeristy of Osaka
    Suita, Osaka, Japan
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.