Clinical trial Recruiting at 1 site Interventional Ages 18 to 70

Active vs Passive Sitting: Testing Cognition, Muscle Use, and Calorie Burn

Official title: Differences in Muscle Utilization, Tissue Pressure, Cognitive Performance, and Caloric Output Among Active and Passive Sitting Positions.

Run by University of Miami · NCT07699848 · Data updated 2026-11-12

Researchers will test how different seated conditions affect thinking speed, muscle use, seated pressure, and calories burned in adults.

Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment35 (estimated)
SponsorUniversity of Miami
Academic / other
Locations1 site (Coral Gables, Florida)
StatusRecruiting
StartedJune 23, 2026
Main results expectedSeptember 30, 2027
Study endsSeptember 30, 2027
Registry record updatedAugust 20, 2026
Trial IDNCT07699848 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults ages 18-70 without current injuries to the lower body or trunk, not taking medications that affect cardiovascular or neuromuscular responses, and without sleep or stress factors that could confound the exercise response.

Probably not a fit

Individuals with current significant cardiovascular, respiratory, neurologic, balance, metabolic, or musculoskeletal conditions or those unable to safely participate in chair-based exercise may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares four seated conditions to see how active versus passive sitting influences cognitive function, muscle activation, soft tissue pressure, and energy expenditure. It uses chair-based exercises to distinguish passive sitting from active dynamic and static exertion. The approach combines electromyography and measurements of seated pressure and caloric output to characterize responses.

Why it matters

Potential benefit: If successful, the results could inform safer, more efficient chair-based activity strategies to support cognition and tissue health.

How similar studies have gone: Prior work in similar chair-based activity protocols has shown measurable changes in muscle activity and energy expenditure, supporting exploration of these conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult (18-70)

Exclusion Criteria:

* Any current injury in the lower limb or trunk.
* Use of prescription drugs or supplements that may affect cardiovascular or neuromuscular responses.
* Reported lack of sleep or stress that may affect physiological responses to exercise.
* Cardiovascular, respiratory, neurologic, balance, metabolic, or musculoskeletal conditions that could increase risk during exercise testing

Where it's running

  • Laboratory of Neuromuscular Research and Active Aging
    Coral Gables, Florida, United States
    Recruiting

Study contacts

  • Principal investigator: Joseph J Signorile, PhD — University of Miami - Coral Gables Campus
  • Study coordinator: Joseph Signorile J Joseph Signorile, PhD
  • Email: jsignorile@miami.edu
  • Phone: 3058981458

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.