Analyzing facial movements in patients with facial palsy and healthy individuals

Multimodal Quantified Analysis of Facial Movements: Comparison Between Pathological

Not applicable Interventional Centre Hospitalier Universitaire, Amiens · NCT05581680

This study is testing how facial movements differ between people with facial palsy and healthy individuals to better understand the impact of the condition.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment720 (estimated)
Ages18 Years and up
SexAll
SponsorCentre Hospitalier Universitaire, Amiens Academic / other
Locations1 site (Amiens, Picardie)
Trial IDNCT05581680 on ClinicalTrials.gov

What this trial studies

This study aims to quantify facial movements in individuals with facial palsy compared to healthy volunteers using advanced techniques such as motion capture and electromyography. By measuring facial mimicry and eye-tracking, the research seeks to provide a detailed analysis of how facial movements are affected by the condition. The study includes both healthy subjects and patients with varying degrees of facial palsy, allowing for a comprehensive comparison of facial function. Participants will undergo dental impressions, simultaneous motion capture, and EMG acquisition, along with follow-up visits for those with facial palsy.

Who should consider this trial

Good fit: Ideal candidates include adults over 18 years old with peripheral facial palsy or healthy volunteers without facial pathology.

Not a fit: Patients with severe skin disorders or speech disorders that hinder participation may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of facial palsy and improve treatment strategies, ultimately leading to better quality of life for affected patients.

How similar studies have performed: While the use of motion capture and electromyography in facial analysis is established, this specific multimodal approach in the context of facial palsy is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects with no known facial pathology (healthy volunteers) OR
* Patients with peripheral facial palsy, irrespective of grade, whether or not previously treated
* Subject with written informed consent
* Subject over 18 years of age
* Subject affiliated to a social security scheme

Exclusion Criteria:

* Subjects with severe skin disorders that do not allow the application of electrodes or photo reflective markers
* Subjects with speech disorders making it impossible to pronounce the sounds \[o\] and \[pu\]
* Subject unable to provide written informed consent
* Subjects under guardianship, curators or safeguard of justice

Where this trial is running

Amiens, Picardie

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions ElectromyographyEye-trackingFacial Palsyfacial mimicsmotion captureelectromyographyeye-tracking
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.