ACT Lung Health Program to help Chinese and Korean American smokers quit
Official title: Efficacy of an Asian Culture-tailored Lung Health (ACT) Intervention on Lung Cancer Screening and Smoking Cessation in Asian Americans
Run by Dana-Farber Cancer Institute · NCT06945120 · Data updated 2026-11-12
This trial tests a counseling and educational program to help Chinese and Korean American smokers at high risk for lung cancer quit smoking.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Dana-Farber Cancer Institute Academic / other |
| Locations | 2 sites (Boston, Massachusetts and 1 other locations) |
| Status | Recruiting |
| Started | November 4, 2025 |
| Main results expected | November 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | March 13, 2026 |
| Trial ID | NCT06945120 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Chinese or Korean American current smokers (≥100 lifetime cigarettes and at least one in the past 30 days), roughly aged 50–80, who speak Korean, Mandarin, or English and will live in the U.S. for the next year.
✕Probably not a fit
People who are pregnant, prisoners, unable to consent, recently hospitalized for serious mental illness, or outside the 50–80 age window are excluded and unlikely to receive benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This two-arm, stratified randomized trial will assign about 50 Chinese and Korean American current smokers at high risk for lung cancer to either the ACT Lung Health Intervention or standard care. Participants will undergo eligibility screening, complete questionnaires, and provide saliva samples, with participation lasting about six months. Eligible participants must self-identify as Chinese or Korean, speak Korean, Mandarin, or English, live in the United States, and meet the smoking history criteria; adults under 50 or over 80, pregnant women, prisoners, and those recently hospitalized for serious mental illness are excluded. The trial is led by Dana-Farber Cancer Institute and University of Massachusetts Boston and is funded by the National Cancer Institute.
Why it matters
Potential benefit: If successful, the program could increase quit rates and reduce lung cancer risk for Chinese and Korean American smokers.
How similar studies have gone: Behavioral counseling and culturally tailored education have improved quit rates in other smoking cessation research, though this specific ACT program for Chinese and Korean Americans is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Self-identify as either Chinese or Korean * Speak either Korean, Mandarin, or English * Are 18 years of age or older * Are current smokers (i.e., have smoked at least 100 traditional cigarettes ever and have smoked at least one traditional cigarette within the prior 30 days) * Will live in the United States for the next 12 months Exclusion Criteria: * Hospitalization due to a serious mental illness (e.g., psychotic disorders) during the prior 6 months. * We will not include any of the following special populations: * Adults unable to consent. * Adults younger than 50 or older than 80 years * Individuals who are not yet adults (infants, children, teenagers) * Pregnant women * Prisoners
Where it's running
-
Dana-Farber Cancer Institute
Boston, Massachusetts, United States Recruiting -
University of Massachusetts-Boston
Boston, Massachusetts, United States Recruiting
Study contacts
- Principal investigator: Mary Cooley, PhD — Dana-Farber Cancer Institute
- Study coordinator: Mary Cooley, PhD
- Email: mary_cooley@dfci.harvard.edu
- Phone: 617-632-5096
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.