ACT Lung Health Program to help Chinese and Korean American smokers quit

Efficacy of an Asian Culture-tailored Lung Health (ACT) Intervention on Lung Cancer Screening and Smoking Cessation in Asian Americans

Not applicable Interventional Dana-Farber Cancer Institute · NCT06945120

This trial tests a counseling and educational program to help Chinese and Korean American smokers at high risk for lung cancer quit smoking.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorDana-Farber Cancer Institute Academic / other
Locations2 sites (Boston, Massachusetts and 1 other locations)
Trial IDNCT06945120 on ClinicalTrials.gov

What this trial studies

This two-arm, stratified randomized trial will assign about 50 Chinese and Korean American current smokers at high risk for lung cancer to either the ACT Lung Health Intervention or standard care. Participants will undergo eligibility screening, complete questionnaires, and provide saliva samples, with participation lasting about six months. Eligible participants must self-identify as Chinese or Korean, speak Korean, Mandarin, or English, live in the United States, and meet the smoking history criteria; adults under 50 or over 80, pregnant women, prisoners, and those recently hospitalized for serious mental illness are excluded. The trial is led by Dana-Farber Cancer Institute and University of Massachusetts Boston and is funded by the National Cancer Institute.

Who should consider this trial

Good fit: Ideal candidates are Chinese or Korean American current smokers (≥100 lifetime cigarettes and at least one in the past 30 days), roughly aged 50–80, who speak Korean, Mandarin, or English and will live in the U.S. for the next year.

Not a fit: People who are pregnant, prisoners, unable to consent, recently hospitalized for serious mental illness, or outside the 50–80 age window are excluded and unlikely to receive benefit from this program.

Why it matters

Potential benefit: If successful, the program could increase quit rates and reduce lung cancer risk for Chinese and Korean American smokers.

How similar studies have performed: Behavioral counseling and culturally tailored education have improved quit rates in other smoking cessation research, though this specific ACT program for Chinese and Korean Americans is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Self-identify as either Chinese or Korean
* Speak either Korean, Mandarin, or English
* Are 18 years of age or older
* Are current smokers (i.e., have smoked at least 100 traditional cigarettes ever and have smoked at least one traditional cigarette within the prior 30 days)
* Will live in the United States for the next 12 months

Exclusion Criteria:

* Hospitalization due to a serious mental illness (e.g., psychotic disorders) during the prior 6 months.
* We will not include any of the following special populations:

  * Adults unable to consent.
  * Adults younger than 50 or older than 80 years
  * Individuals who are not yet adults (infants, children, teenagers)
  * Pregnant women
  * Prisoners

Where this trial is running

Boston, Massachusetts and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Smoking CessationSmoking BehaviorsSmoking, TobaccoSmoking, CigaretteSmoking AddictionLung Cancer Screening
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.