Accelerated rTMS for treating neuropathic pain
Analgesic Effect of Accelerated Repetitive Transcranial Magnetic Stimulation in Pain Related to Peripheral Neuropathy
NA · Jagiellonian University · NCT05295498
This study is testing a new way of using brain stimulation to see if it can help people with chronic nerve pain feel better faster.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Jagiellonian University (other) |
| Locations | 1 site (Krakow) |
| Trial ID | NCT05295498 on ClinicalTrials.gov |
What this trial studies
This study investigates the feasibility of using accelerated repetitive Transcranial Magnetic Stimulation (rTMS) to alleviate neuropathic pain associated with peripheral neuropathy. rTMS is a noninvasive technique that modulates brain activity through magnetic stimuli delivered to the cerebral cortex. Unlike traditional rTMS, which is administered once daily over a week, this approach involves multiple sessions per day to potentially enhance therapeutic effects and reduce treatment duration. The study aims to assess the effectiveness and practicality of this accelerated method in patients suffering from chronic neuropathic pain.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with peripheral neuropathy experiencing constant neuropathic pain requiring analgesics more than once a week.
Not a fit: Patients with severe depression, cognitive deficits, or other psychiatric conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a new, effective non-drug treatment option for patients with chronic neuropathic pain.
How similar studies have performed: Other studies have shown promising results with rTMS for various conditions, suggesting potential for success with this accelerated approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of peripheral neuropathy * Neuropathic pain of constant severity since not less than a month and requiring use of analgesics more than once a week * Score of 30 millimeter or more on the 100 millimeter visual analog scale of pain intensity at inclusion Exclusion Criteria: * Severe depression * Personality disorders and other psychiatric conditions, which could disturb the participation in the study * Cognitive deficits, which could disturb the participation in the study * Epilepsy * Presence of magnetic material in the reach of magnetic field * Pregnancy * Likelihood to get pregnant * Intracranial electrodes
Where this trial is running
Krakow
- Jagiellonian University Medical College — Krakow, Poland (RECRUITING)
Study contacts
- Study coordinator: Jakub M Antczak, MD
- Email: jakub.antczak@uj.edu.pl
- Phone: +48 795 421 153
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Peripheral Neuropathy, Peripheral neuropathy, Neuropathic pain, rTMS, analgesic effect