A program to help young Black men who have sex with men prevent HIV

An Acceptance Based PrEP Intervention to Engage Young Black MSM in the South

Not applicable Interventional Rhode Island Hospital · NCT05087680

This study is testing a new program to help young Black men who have sex with men take a medication to prevent HIV and see if it works better than the usual care they receive.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment66 (estimated)
Ages18 Years to 34 Years
SexMale
SponsorRhode Island Hospital Academic / other
Locations1 site (Jackson, Mississippi)
Trial IDNCT05087680 on ClinicalTrials.gov

What this trial studies

This intervention focuses on developing a culturally appropriate pre-exposure prophylaxis (PrEP) program called ACTPrEP, specifically designed for young Black men who have sex with men (YBMSM). The study will gather qualitative data from participants and clinic staff to inform the intervention's design and assess its feasibility and acceptability. Participants will be enrolled to evaluate the effectiveness of ACTPrEP compared to enhanced standard of care over a 24-week period, measuring outcomes such as PrEP uptake and adherence. The study aims to identify barriers and facilitators to implementing the intervention through qualitative interviews.

Who should consider this trial

Good fit: Ideal candidates are English-speaking Black men aged 18-34 who have had sex with a man in the past three months and are eligible for PrEP.

Not a fit: Patients who are currently enrolled in another PrEP study or have taken PrEP in the past three months may not benefit from this intervention.

Why it matters

Potential benefit: If successful, this intervention could significantly improve HIV prevention strategies among young Black MSM.

How similar studies have performed: Other studies have shown promise in using culturally tailored interventions for HIV prevention, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English speaking
* Between 18-34 years old
* Male sex assigned at birth
* Identify as African American/Black
* Not enrolled in another PrEP related study
* Able to give consent
* Not taken PrEP in past 3 months
* Report having sex with a man in the past 3 months
* PrEP-eligible according to CDC guidelines

Exclusion Criteria:

* Participating in another PrEP study
* Unable to provide consent

Where this trial is running

Jackson, Mississippi

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HIV PreventionACTPrEP
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.