A new approach to diagnosing and treating heart attacks
Time for a DIagnostic Paradigm Shift From ST-elevation/Non-ST-elevation to OCClUsion/Non-occLusion Myocardial infarcTion
NA · Başakşehir Çam & Sakura City Hospital · NCT06570759
This study tests a new way to diagnose and treat heart attacks to see if it can help doctors better identify the type of heart attack and improve outcomes for patients.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 6000 (estimated) |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Sponsor | Başakşehir Çam & Sakura City Hospital (other gov) |
| Locations | 18 sites (Ankara and 17 other locations) |
| Trial ID | NCT06570759 on ClinicalTrials.gov |
What this trial studies
This study investigates a new diagnostic approach for myocardial infarction (MI) that distinguishes between occlusion myocardial infarction (OMI) and non-occlusion myocardial infarction (NOMI). The goal is to improve the identification of acute coronary occlusion and optimize treatment strategies, potentially leading to better patient outcomes. Participants will receive either early intervention for OMI or standard interventions for STEMI and NSTEMI. The study aims to evaluate the effectiveness of this new paradigm in reducing infarct size and improving long-term cardiac health.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old with an ECG and/or clinical diagnosis of acute myocardial infarction.
Not a fit: Patients who are pregnant, have non-ischemic myocardial injury, or have received thrombolytic therapy instead of primary PCI may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate diagnoses and better treatment outcomes for patients experiencing heart attacks.
How similar studies have performed: While this approach is novel, previous studies have indicated that refining diagnostic criteria can lead to improved patient outcomes in acute coronary syndromes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria * Age \>18 years * ECG and/or clinical diagnosis of acute myocardial infarction Exclusion criteria * Active pregnancy or a suspicion of pregnancy * Rejection or withdrawal of consent * Failure to acquire any of the pre-participation ECGs * Non-ischemic myocardial injury * Application of thrombolytic therapy instead of primary PCI * Re-occlusion of the culprit lesion after intervention\* * New vessel occlusion during hospital stay\* * Exclusion from final analyses.
Where this trial is running
Ankara and 17 other locations
- Ankara Etlik City Hospital — Ankara, Turkey (RECRUITING)
- Antalya City Hospital — Antalya, Turkey (RECRUITING)
- Erzurum Atatürk University Hospital — Erzurum, Turkey (RECRUITING)
- Eskisehir Osmangazi University Hospital — Eskişehir, Turkey (RECRUITING)
- Eskişehir City Hospital — Eskişehir, Turkey (RECRUITING)
- Mehmet Akif Ersoy Cardiovascular and Throacic Training and Research Hospital — Istanbul, Turkey (RECRUITING)
- Basaksehir Cam and Sakura City Hospital — Istanbul, Turkey (RECRUITING)
- Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital — Istanbul, Turkey (RECRUITING)
- Kartal Kosuyolu Training and Research Hospital — Istanbul, Turkey (ACTIVE_NOT_RECRUITING)
- Marmara University, Pendik Training and Research Hospital — Istanbul, Turkey (RECRUITING)
- Bağcılar Training and Research Hospital — Istanbul, Turkey (RECRUITING)
- Necmettin Erbakan Meram Tıp Fakültesi Hastanesi — Konya, Turkey (RECRUITING)
- Kutahya Health Sciences University — Kütahya, Turkey (RECRUITING)
- Mugla Sitki Kocman University — Muğla, Turkey (RECRUITING)
- Tokat Gaziosmanpaşa University — Tokat, Turkey (RECRUITING)
- Yuzuncu Yil University Hospital — Van, Turkey (RECRUITING)
- Van Training and Research Hospital — Van, Turkey (RECRUITING)
- Sirnak State Hospital — Şırnak, Turkey (RECRUITING)
Study contacts
- Study coordinator: Emre K Aslanger, Prof
- Email: mr_aslanger@hotmail.com
- Phone: +90 (212) 909 60 00
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Myocardial Infarction, Myocardial Ischemia, Acute Coronary Syndrome, Diagnosis, Morality