A comprehensive database for cancer patient genomic and clinical data

BostonGene-Integrated Genomic Registry Study

Observational BostonGene · NCT04991922

This study is creating a detailed database of cancer patients' genetic and health information to see if it can help improve treatment outcomes for different types of cancer.

Quick facts

Study typeObservational
Enrollment100000 (estimated)
Ages18 Years and up
SexAll
SponsorBostonGene Industry-sponsored
Locations1 site (Waltham, Massachusetts)
Trial IDNCT04991922 on ClinicalTrials.gov

What this trial studies

This project aims to create a detailed registry that compiles genomic, transcriptomic, molecular, and clinical characteristics of oncology patients. By collecting and analyzing this data, the study seeks to identify genomic and transcriptomic markers that can enhance clinical outcomes across various cancer types. Participants will provide clinical information linked to their genetic findings, which will be stored in a secure electronic database. The study does not involve any additional scans or procedures beyond standard care.

Who should consider this trial

Good fit: Ideal candidates include individuals with suspected or confirmed malignancy who are undergoing comprehensive genomic analysis.

Not a fit: Patients with a life expectancy of less than three months may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies and outcomes for cancer patients through personalized medicine.

How similar studies have performed: Other studies have shown promise in utilizing genomic and transcriptomic data to improve cancer treatment outcomes, indicating that this approach is supported by prior research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Suspected or confirmed malignancy
2. Planned comprehensive genomic (\> 100 genes) and/or molecular analysis; or genomic and/or molecular data available from prior sequencing
3. Baseline demographics and treatment information available
4. Willingness for future contact by BIRG study personnel to provide information regarding associated cancer outcomes and treatment.
5. Signed informed consent to participate in the study.
6. Living in the United States at the time of enrollment

Exclusion Criteria:

Life expectancy \< 3 months

Where this trial is running

Waltham, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Malignancycancerprecision medicineWESRNA-seqimmuno-therapygenomictranscriptomic
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.