6 Weeks of Blood Flow Restriction Training With Walking for Type 2 Diabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with type 2 diabetes will be randomized to 6 weeks of regular treadmill walking or treadmill walking with blood flow restriction. Both groups walk three times per week, starting at 21 minutes and increasing to 32 minutes per session, guided to reach 40-50% heart rate reserve. The BFR group will have cuffs inflated to individualized limb occlusion pressure, remaining inflated during the session with brief deflations for safety, and pressure increased each week from 60% to 80% LOP. Outcomes are measured at baseline and after the 6-week intervention to assess immune cell function and bioenergetics. The trial is conducted at the University of British Columbia Okanagan with local participation restricted to eligible adults aged 19-64.

Why it matters

Who can join: the full rules

Inclusion Criteria:

A. Aged 19-64 years. B. Diagnosed with type 2 diabetes with current HbA1c 5.7-9.0% C. Completing \<150 minutes of moderate-vigorous physical activity per week.

Exclusion Criteria:

A. Chronic musculoskeletal condition or recent (within 2 years) cardiovascular event preventing participation in exercise.

B. Unstable type 2 diabetes medication of the last 3 months C. Absolute contraindications to BFR (i.e., peripheral vascular disease) D. A self-reported diagnosis of low iron concentrations, anemia, or being treated for these conditions E. A diagnosis of any red blood cell-altering condition (i.e., sickle cell anemia, poikilocytosis) F. Currently living with any cardiovascular disease, which would impact the ability to participate in exercise safely G. Currently prescribed any medication which would impact the ability to use a heart rate monitor to accurately track intensity

Where it's running

• University of British Columbia Okanagan
  Kelowna, British Columbia, Canada Recruiting

Study contacts

• Study coordinator: Jonathan P Little, PhD
• Email: jonathan.little@ubc.ca
• Phone: 250-807-9876

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.