3D Computer-Assisted Workflow for Diagnosing and Correcting Facial Deformities
Official title: Full-3D Computer-Assisted Workflow for the Diagnosis and Correction of Deformities? Dentofacial
Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06806605 · Data updated 2026-11-12
This study is testing a new 3D computer system to see if it can help doctors better diagnose and fix facial deformities in patients who need surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna, Emilia-Romagna) |
| Status | Recruiting |
| Started | January 11, 2020 |
| Main results expected | September 11, 2026 |
| Study ends | November 11, 2026 |
| Registry record updated | February 4, 2025 |
| Trial ID | NCT06806605 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 to 60 with dentoskeletal dysmorphia who are scheduled for orthognathic surgery.
✕Probably not a fit
Patients who have previously undergone facial surgeries during the treatment period may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on the diagnosis and correction of dentofacial deformities using a full 3D computer-assisted workflow. It involves the integration of advanced imaging techniques and surgical planning to improve outcomes for patients undergoing orthognathic surgery. The approach aims to enhance the precision of surgical interventions by utilizing technologies such as multislice CT, cone beam CT, and CAD-CAM. Patients with significant skeletal discrepancies that cannot be resolved through orthodontics alone will be evaluated for this innovative treatment method.
Why it matters
Potential benefit: If successful, this approach could significantly improve the functional and aesthetic outcomes for patients with dentofacial deformities.
How similar studies have gone: Other studies utilizing advanced imaging and surgical planning techniques have shown promising results, indicating that this approach is supported by prior successful methodologies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with dentoskeletal dysmorphia. * Patients undergoing orthognathic surgery. * Patients between 18 and 60 years of age at the time of orthognathic surgery. * Obtaining informed consent.Inclusion criteria * Patients with dentoskeletal dysmorphia. * Patients undergoing orthognathic surgery. * Patients between 18 and 60 years of age at the time of orthognathic surgery. * Obtaining informed consent. Exclusion Criteria: * Patients who have undergone other facial surgeries during the treatment period. * Patients who have not followed the data collection phases foreseen in the 3D Study.
Where it's running
-
IRCCS - Azienda Ospedaliero Universitaria di Bologna
Bologna, Emilia-Romagna, Italy Recruiting
Study contacts
- Principal investigator: Claudio Marchetti, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Claudio Marchetti, MD
- Email: claudio.marchetti@aosp.bo.it
- Phone: 051 241 8362
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
3D-Printed vs. Milled Titanium Plates for Le Fort I Jaw Surgery
This study tests whether 3D-printed patient-specific titanium plates improve surgical accuracy and reduce operation time compared with milled plates in Le Fort I jaw surgery.
-
Changes in Depression and How Patients Perceive Their Appearance After Double-Jaw Orthognathic Surgery
This study tests whether undergoing bimaxillary orthognathic surgery changes depressive symptoms and self-perceived facial appearance in adults with dentofacial deformities.
-
Pre-surgery anxiety and its effects on heart rate, blood pressure, pain, swelling, and mouth opening after orthognathic (jaw) surgery
This will see if higher anxiety before bimaxillary orthognathic surgery leads to bigger changes in heart rate and blood pressure during the operation and to more pain, facial swelling, or limited mouth opening afterward.
-
Custom 3D-printed guide versus manual positioning for the proximal mandibular segment in sagittal split ramus osteotomy
This study will try a custom 3D-printed positioning guide on one side of the jaw and the surgeon's usual manual positioning on the other side in adults having sagittal split ramus osteotomy to see if the guide improves positioning accuracy and short-term outcomes.
-
Evaluating attention to faces after jaw surgery using eye-tracking
This study is testing how jaw surgery affects the way people look at faces, to see if it changes their social interactions after the surgery.
-
Analyzing speech changes in jaw surgery patients
This study looks at how jaw surgery affects the way people speak by recording their speech and tongue movements before and after the surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.