20% Lower Bupivacaine Dose May Cut High Spinal Block in Cesarean Deliveries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind study compares a reduced-dose intrathecal hyperbaric bupivacaine regimen (10 mg) to a standard-dose regimen (12.5 mg) in women undergoing cesarean delivery. Participants are stratified by a preoperative risk-prediction model before randomization to evaluate whether dose awareness affects outcomes. The primary outcome is the incidence of high spinal block, with both groups receiving concurrent fentanyl to standardize analgesia. The trial is conducted at Aswan University, enrolling ASA II-III pregnant patients aged 18-45 without twin pregnancies or contraindications to spinal anesthesia. Results may clarify if a smaller dose can maintain anesthesia safety while reducing adverse block levels.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* • Pregnant women aged 18-45 years.

  * ASA physical status II-III.

Exclusion Criteria:

* • Twin pregnancies.

  * Contraindications to spinal anesthesia (e.g., coagulopathy, infection).
  * Patients with incomplete preoperative data for risk stratification.

Where it's running

• Aswan university
  Aswān, Aswan Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Eman Mahmoud Ismail, Resident
• Email: emanmahmoud37@gmail.com
• Phone: +201141431136

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Improving pain control after cesarean section with nerve blocks

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.