1:4 Reishi liquid extract for improving sleep quality
Official title: The Effects on Sleep Quality of 1:4 Reishi Liquid Extract
Run by Efforia, Inc · NCT07294482 · Data updated 2026-11-12
This study will test whether taking 1 ml of a 1:4 Reishi mushroom liquid extract 30 minutes before bed helps adults in the U.S. sleep better and feel less stressed.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Efforia, Inc Industry-sponsored |
| Locations | 1 site (New York, New York) |
| Status | Recruiting |
| Started | September 10, 2025 |
| Main results expected | September 10, 2026 |
| Study ends | September 10, 2026 |
| Registry record updated | December 26, 2025 |
| Trial ID | NCT07294482 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult U.S. residents who can read English, can follow the protocol, and do not meet exclusion criteria such as pregnancy, anticoagulant use, immunocompromise, liver disease, chronic illness, mental health disorders, or mushroom allergies.
✕Probably not a fit
Those who are pregnant or nursing, on blood thinners, immunocompromised, have liver disease, chronic illnesses, mental health disorders, or mushroom allergies are excluded and therefore unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a remotely administered, decentralized interventional study testing daily use of a 1:4 Reishi liquid extract taken 30 minutes before bedtime. Participants will self-administer 1 ml of the tincture each night and report sleep metrics including duration, sleep onset latency, nighttime awakenings, and perceived restfulness, along with daytime energy and perceived stress. Data are collected remotely and participants receive individualized feedback on how the tincture affects their sleep patterns. The trial excludes people with certain medical conditions or medication use that could raise safety concerns and is open to English-reading U.S. residents who can follow the protocol.
Why it matters
Potential benefit: If successful, the Reishi tincture could modestly increase sleep duration, reduce nocturnal awakenings, and lower perceived stress for some users.
How similar studies have gone: There is limited preliminary and animal data and some small human reports suggesting calming or sleep-promoting effects of Reishi, but well-powered randomized human trials are lacking.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Can read and understand English. * US resident. * Willing and able to follow the requirements of the protocol. Exclusion Criteria: * Individuals with Allergies * Pregnant or Nursing Women * Individuals on Anticoagulants * Immunocompromised Individuals * Individuals with Liver Disease * Children and Adolescents * Individuals with Chronic Illnesses * Those with Mental Health Disorders
Where it's running
-
Efforia
New York, New York, United States Recruiting
Study contacts
- Study coordinator: Matthew Amsden
- Email: help@efforia.com
- Phone: 646-679-2479
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.