Leptin-supporting supplement for hunger and weight-related changes
Evaluation of Hunger Perception and Weight-Related Outcomes Following Use of a Leptin-Supporting Dietary Supplement Over 12 Weeks
This project tests whether taking a leptin-supporting dietary supplement daily for 12 weeks changes hunger feelings and body-weight related measures in adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Efforia, Inc Industry-sponsored |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT07442864 on ClinicalTrials.gov |
What this trial studies
This single-group, prospective observational study asks adults to self-administer a commercially available supplement called Leptin Balance Formula for 12 weeks while completing electronic questionnaires and self-reported measurements. Participants serve as their own controls, with comparisons made between baseline and follow-up measures of hunger perception and body composition–related outcomes. The study is open-label and designed as signal-detection in a general wellness context rather than a controlled clinical efficacy trial. Results are intended to generate preliminary, real-world evidence to inform future, more rigorous research.
Who should consider this trial
Good fit: Adults aged 18 or older who can take the supplement daily for 12 weeks, are willing to pay for study supplies, and can complete electronic questionnaires and self-reported measurements are the intended participants.
Not a fit: People who are pregnant or breastfeeding, allergic to supplement ingredients, using medications or other supplements that affect appetite or weight without medical clearance, or who have medical conditions making participation unsafe may not receive benefit.
Why it matters
Potential benefit: If successful, this could suggest an accessible supplement option to help some people better manage hunger sensations and weight-related measures.
How similar studies have performed: Some individual ingredients (like chromium, cinnamon, and alpha-lipoic acid) have produced mixed or limited findings in prior smaller studies, so this specific combination and real-world format are not yet proven in rigorous trials.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 years or older * Willing to pay for study supplies and able to take the dietary supplement daily for 12 weeks * Willing to complete electronic questionnaires and self-reported measurements * Able to provide informed consent Exclusion Criteria: * Pregnant or breastfeeding individuals * Known allergy or sensitivity to any supplement ingredients * Use of medications or supplements that could interfere with appetite or weight without medical clearance * Any medical condition that would make participation unsafe, as determined by the participant
Where this trial is running
New York, New York
- Efforia — New York, New York, United States (Recruiting)
Study contacts
- Study coordinator: Matthew Amsden
- Email: help@efforia.com
- Phone: 646-679-2479
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.