Leptin-supporting supplement for hunger and weight-related changes
Official title: Evaluation of Hunger Perception and Weight-Related Outcomes Following Use of a Leptin-Supporting Dietary Supplement Over 12 Weeks
Run by Efforia, Inc · NCT07442864 · Data updated 2026-11-12
This project tests whether taking a leptin-supporting dietary supplement daily for 12 weeks changes hunger feelings and body-weight related measures in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Efforia, Inc Industry-sponsored |
| Locations | 1 site (New York, New York) |
| Status | Recruiting |
| Started | September 10, 2025 |
| Main results expected | September 10, 2026 |
| Study ends | September 10, 2026 |
| Registry record updated | March 2, 2026 |
| Trial ID | NCT07442864 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older who can take the supplement daily for 12 weeks, are willing to pay for study supplies, and can complete electronic questionnaires and self-reported measurements are the intended participants.
✕Probably not a fit
People who are pregnant or breastfeeding, allergic to supplement ingredients, using medications or other supplements that affect appetite or weight without medical clearance, or who have medical conditions making participation unsafe may not receive benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-group, prospective observational study asks adults to self-administer a commercially available supplement called Leptin Balance Formula for 12 weeks while completing electronic questionnaires and self-reported measurements. Participants serve as their own controls, with comparisons made between baseline and follow-up measures of hunger perception and body composition–related outcomes. The study is open-label and designed as signal-detection in a general wellness context rather than a controlled clinical efficacy trial. Results are intended to generate preliminary, real-world evidence to inform future, more rigorous research.
Why it matters
Potential benefit: If successful, this could suggest an accessible supplement option to help some people better manage hunger sensations and weight-related measures.
How similar studies have gone: Some individual ingredients (like chromium, cinnamon, and alpha-lipoic acid) have produced mixed or limited findings in prior smaller studies, so this specific combination and real-world format are not yet proven in rigorous trials.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 years or older * Willing to pay for study supplies and able to take the dietary supplement daily for 12 weeks * Willing to complete electronic questionnaires and self-reported measurements * Able to provide informed consent Exclusion Criteria: * Pregnant or breastfeeding individuals * Known allergy or sensitivity to any supplement ingredients * Use of medications or supplements that could interfere with appetite or weight without medical clearance * Any medical condition that would make participation unsafe, as determined by the participant
Where it's running
-
Efforia
New York, New York, United States Recruiting
Study contacts
- Study coordinator: Matthew Amsden
- Email: help@efforia.com
- Phone: 646-679-2479
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Nutritional Pack Intervention to Reduce Hunger and Improve Concentration in Schoolchildren
This study tests whether giving nutritional supplement packs to students in grades 3–9 in rural schools helps reduce hunger, promote healthy eating, and improve classroom concentration.
-
Recovery after stopping semaglutide: effects on weight, heart risk, and appetite
This trial will test whether gradually lowering semaglutide instead of stopping it suddenly changes weight, heart risk markers, and appetite hormones in adults with obesity who lost at least 10% of their weight on semaglutide.
-
Remote app monitoring for people with chronic heart failure
It will test whether using a smartphone telemonitoring app for people with chronic heart failure to report blood pressure and body weight helps support care and detect problems earlier.
-
Integrated Childhood Activity and Nutrition (ICAN) program to prevent summer learning loss
This 8-week program will try daily lutein-rich snacks plus group physical activities to see if they help prevent summer learning loss and support thinking skills and fitness in 6–11-year-old children from low-income families.
-
Optimizing extended care to help people keep weight off
This program will test which combination of four low‑burden supports helps adults with obesity who have lost weight keep that weight off.
-
Improving nutrition education for children and parents facing food insecurity
This study is testing a new way to help children and their parents who use food assistance improve their eating habits and food security over time.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.