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Clinical trials and research at Regina Elena Cancer Institute

• 29Clinical trials
• 1Country

Newest trials

All recruiting trials (29)

• Focal Micro-boost Radiotherapy for Localized Prostate Cancer

  This study tests whether adding a small, targeted boost to MRI-visible prostate lesions during moderately hypofractionated radiotherapy can improve cancer control in men with localized intermediate- to high-risk prostate cancer.

  Recruiting Regina Elena Cancer Institute · Rome, Lazio · NCT07792993

• Liquid biopsy at diagnosis for advanced NSCLC

  We’re testing whether a blood test (liquid biopsy) done early can speed up getting usable molecular information for adults with suspected advanced NSCLC.

  Recruiting Regina Elena Cancer Institute · Roma, RM · NCT07649629

• Immune Metabolism in NSCLC and Response to PD-1/PD-L1 Inhibitors

  This observational study will look at metabolic patterns in tumor and immune cells from NSCLC patients to see if they correlate with response or resistance to PD-1/PD-L1 therapies.

  Recruiting Regina Elena Cancer Institute · Rome, Rome · NCT07637474

• Standardizing patient-derived models to test microencapsulated nutraceuticals with immunotherapy in NSCLC

  Doctors will test microencapsulated nutraceuticals derived from resveratrol and artichoke extract in preclinical NSCLC models made from patients’ tumor tissue to see if they boost immunotherapy.

  Recruiting Regina Elena Cancer Institute · Rome, Rome · NCT07629375

• Creating organoids from endometrial cancer tissue

  We will try to grow miniature tumor models (organoids) from surgical tissue of adults with endometrial cancer to see if transport and handling affect whether they can be grown.

  Recruiting Regina Elena Cancer Institute · Roma, Roma · NCT07258186

• Vitamin K, d‑chiro‑inositol and α‑lactalbumin for protecting bones during breast cancer hormone therapy

  This will test whether adding vitamin K, d‑chiro‑inositol and α‑lactalbumin to calcium and vitamin D better protects bone health in women on hormone therapy for breast cancer.

  Recruiting Regina Elena Cancer Institute · Latina, Italy and 1 other locations · NCT07256769

• Growing cervical cancer organoids from diagnostic biopsy samples

  We will try to grow tiny, patient-specific tumor organoids from biopsy tissue collected during diagnostic biopsy in adults with suspected stage IB2–IIIA cervical cancer so labs can test treatments on them.

  Recruiting Regina Elena Cancer Institute · Roma, RM · NCT07248878

• Tracking TTV viral load during first-line immunotherapy for renal cell carcinoma

  This project will test whether changes in torquetenovirus (TTV) levels in blood and stool can help predict how people with metastatic clear cell renal cell carcinoma respond to first-line immunotherapy.

  Recruiting Regina Elena Cancer Institute · Rome, Rome · NCT07018037

• Investigating urinary microbiome differences in bladder cancer and healthy men

  This study looks at the differences in bacteria found in the urine of men with bladder cancer, those with other urinary issues, and healthy men to see if these differences are linked to bladder cancer.

  Recruiting Regina Elena Cancer Institute · Rome · NCT06992986

• Combining fractionated stereotactic radiosurgery with surgery for brain metastases

  This study is testing whether giving radiation therapy before surgery can help people with brain tumors from cancers like lung, breast, and melanoma have better outcomes and fewer complications.

  Recruiting Regina Elena Cancer Institute · Rome · NCT06992973

• Evaluating genomic testing and radiotherapy for prostate cancer recurrence

  This study is testing if a genomic test can help guide radiation treatment for men whose prostate cancer comes back after surgery.

  Recruiting Regina Elena Cancer Institute · Roma · NCT06894628

• Examining miRNA Signatures in Glioma for Clinical Use

  This study is testing how certain tiny molecules in the body affect glioma tumors and their response to treatments like radiation and a common chemotherapy drug, to help improve care for glioma patients.

  Recruiting Regina Elena Cancer Institute · Rome, Rome · NCT06883214

• Improving blood management for breast cancer patients undergoing surgery

  This study tests whether giving iron treatment before surgery can help breast cancer patients with low hemoglobin levels need fewer blood transfusions during their operations.

  Recruiting Regina Elena Cancer Institute · Rome · NCT06883201

• Analyzing urine methylation patterns for early bladder cancer diagnosis

  This study is testing if checking for specific changes in urine can help doctors find bladder cancer earlier and more accurately.

  Recruiting Regina Elena Cancer Institute · Rome · NCT06878027

• Exploring how couples cope with breast cancer

  This study looks at how couples handle the challenges of breast cancer over two years to see what helps them cope and stay strong together.

  Recruiting Regina Elena Cancer Institute · Roma, Rome · NCT06875414

• Using AI to predict risks in endometrial cancer management

  This study is testing if using artificial intelligence can help doctors better predict risks and improve treatment for women with endometrial cancer, especially to help preserve fertility in those with low-risk profiles.

  Recruiting Regina Elena Cancer Institute · Rome · NCT06841653

• Exploring biomarkers in patients with HPV-related head and neck cancer

  This study looks at patients with HPV-related throat cancer to see how their body responds to treatment by checking their blood and tissue samples for HPV and immune markers.

  Recruiting Regina Elena Cancer Institute · Rome, Rome · NCT06821243

• Molecular diagnosis of lung cancer response to immunotherapy

  This study is trying to see how the genes in lung cancer tumors affect how well patients respond to immunotherapy, with the hope of improving personalized treatment options.

  Recruiting Regina Elena Cancer Institute · Rome · NCT06807307

• Understanding how mutant p53/YAP proteins affect treatment resistance in head and neck cancer

  This study looks at how changes in certain proteins in head and neck cancer cells might make them resistant to treatment, helping doctors find better ways to fight the disease.

  Recruiting Regina Elena Cancer Institute · Roma, Rome · NCT06791941

• Creating organoids from colorectal tumors and liver metastases

  This study is trying to create mini versions of colorectal tumors and their liver spread to see how certain genes work and find new ways to treat cancer.

  Recruiting Regina Elena Cancer Institute · Rome · NCT06787625

• Creating organoid cultures from male breast tumors

  This study is trying to grow mini versions of male breast tumors from patients to see how well they match the original tumors and how they respond to treatments.

  Recruiting Regina Elena Cancer Institute · Rome · NCT06786663

• Combining radiotherapy with immunotherapy for extensive small cell lung cancer

  This study is testing if combining radiation therapy with a type of immunotherapy can help people with extensive small cell lung cancer live longer after their initial treatment.

  Recruiting Phase 2 Regina Elena Cancer Institute · Rome, Rome · NCT06771518

• Treatment for indeterminate thyroid nodules using myo-inositol and selenium

  This study is testing if a six-month treatment with a supplement of myo-inositol and selenium can help reduce the size and improve the elasticity of certain thyroid nodules in patients.

  Recruiting Regina Elena Cancer Institute · Rome · NCT06736015

• Using shockwave therapy to improve erectile function after prostate cancer surgery

  This study is testing whether using shockwave therapy along with a common erectile dysfunction medication can help men regain erectile function better after prostate cancer surgery.

  Recruiting at 2 sites Phase 3 Regina Elena Cancer Institute · Rome, RM and 1 other locations · NCT06717711

• Evaluating flap use in laryngectomy after failed cancer treatment

  This study is testing if using a special flap during surgery for throat cancer helps reduce the risk of complications and improves recovery for patients who have already had treatment that didn't work.

  Recruiting Regina Elena Cancer Institute · Rome, Rome · NCT06287034

• Evaluating the effectiveness of sacituzumab govitecan for metastatic triple-negative breast cancer

  This study is testing how well a new treatment called sacituzumab govitecan works for people with metastatic triple-negative breast cancer and whether it is safe to use.

  Recruiting Regina Elena Cancer Institute · Rome, Rome · NCT06240195

• New method for detecting melanoma biomarkers in blood samples

  This study is testing a new blood test that looks for specific markers of melanoma to see if it works better than current methods.

  Recruiting Regina Elena Cancer Institute · Rome · NCT05940311

• Observing viral biomarkers and microRNAs in oropharyngeal tumors and occult cancers related to HPV

  This study is testing if certain viral markers and microRNAs in oropharyngeal tumors can help doctors better diagnose and monitor HPV-related cancers and find new treatments.

  Recruiting Regina Elena Cancer Institute · Rome · NCT05918510

• Combining SBRT with short-term androgen deprivation for high-risk prostate cancer

  This study is testing whether adding a short-term hormone treatment to a type of targeted radiation can help men with high-risk prostate cancer do better than just using radiation alone.

  Recruiting at 3 sites Phase 2 Regina Elena Cancer Institute · Rome, Lazio and 2 other locations · NCT05557604

Quick answers

How many clinical trials run by Regina Elena Cancer Institute are recruiting right now?

29, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in Italy. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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