Sponsor or institution

Clinical trials and research at Ono Pharmaceutical Co., Ltd.

• 16Clinical trials
• 15Countries

Newest trials

All recruiting trials (16)

• ONO-7429 in advanced or recurrent solid tumors

  This small early-phase study tests whether ONO-7429 is tolerable and safe in adults with unresectable advanced or recurrent solid tumors who have tried other treatments.

  Recruiting at 10 sites Phase 1 Ono Pharmaceutical Co., Ltd. · Kashiwa, Chiba and 9 other locations · NCT07787208

• ONO-6414 safety and PK in healthy adults and adults with active ulcerative colitis

  This study tests the safety, tolerability, and how ONO-6414 behaves in the body when taken by healthy adults and adults with active ulcerative colitis.

  Recruiting Phase 1 Ono Pharmaceutical Co., Ltd. · Miami, Florida · NCT07749768

• ONO-4538HSC in children with solid tumors or epithelioid sarcoma

  This study tests ONO-4538HSC in kids with malignant solid tumors or epithelioid sarcoma to see if it is tolerable and may help with the disease.

  Recruiting at 6 sites Phase 1/2 Ono Pharmaceutical Co., Ltd. · Chiba, Chiba and 14 other locations · NCT07734116

• ONO-3310 safety test in healthy men and adults with CKD and type 2 diabetes

  This early-phase study tests whether ONO-3310 is safe and well tolerated in healthy Japanese men and in adults with chronic kidney disease and type 2 diabetes, using single and multiple oral doses.

  Recruiting Phase 1 Ono Pharmaceutical Co., Ltd. · Fukuoka, Fukuoka · NCT07619157

• DCC-2618 in GIST after at least 3 prior treatments

  This trial tests whether DCC-2618 is safe in people with advanced GIST who have already tried at least three other treatments.

  Recruiting at 2 sites Phase 1 Ono Pharmaceutical Co., Ltd. · Kashiwa, Chiba and 1 other locations · NCT07618377

• Kid-focused cenobamate for partial seizures in kids 2 to 17

  This study tests cenobamate to see if it is safe and helps reduce seizures in Japanese children and teens aged 2 to 17 with partial-onset epilepsy.

  Recruiting Phase 3 Ono Pharmaceutical Co., Ltd. · Fukuoka · NCT07594158

• Sapablursen added to standard care for people with polycythemia vera

  This trial will test whether adding sapablursen to standard therapy can reduce the need for phlebotomy in people with polycythemia vera who remain phlebotomy-dependent.

  Recruiting at 38 sites Phase 3 Ono Pharmaceutical Co., Ltd. · Orange, California and 37 other locations · NCT07429266

• Nivolumab with chemotherapy as neoadjuvant therapy for resectable NSCLC in Taiwan

  This real-world study tests whether adding nivolumab to chemotherapy before surgery helps people with NSCLC in Taiwan.

  Recruiting at 9 sites Ono Pharmaceutical Co., Ltd. · Kaohsiung City and 8 other locations · NCT07169708

• Tirabrutinib versus rituximab plus temozolomide for relapsed or refractory primary central nervous system lymphoma

  This trial tests whether the oral drug tirabrutinib works better alone than the combination of rituximab and temozolomide for people with relapsed or refractory primary CNS lymphoma.

  Recruiting at 42 sites Phase 3 Ono Pharmaceutical Co., Ltd. · Phoenix, Arizona and 41 other locations · NCT07104032

• Two-dose ONO-4578 with Opdivo plus mFOLFOX6 and bevacizumab versus standard treatment for advanced PD-L1–positive colorectal cancer

  This trial tests whether adding one of two doses of ONO-4578 to Opdivo, standard chemotherapy (mFOLFOX6), and bevacizumab helps people with PD-L1–positive, non-MSI-H advanced colorectal cancer as their first-line treatment.

  Recruiting at 39 sites Phase 2 Ono Pharmaceutical Co., Ltd. · Phoenix, Arizona and 38 other locations · NCT06948448

• ONO-4538 treatment for Richter's transformation

  This trial will test if the drug ONO-4538 works and is safe for people whose CLL/SLL has transformed into Richter's transformation (DLBCL- or Hodgkin-type).

  Recruiting at 10 sites Phase 2 Ono Pharmaceutical Co., Ltd. · Nagoya, Aichi-ken and 9 other locations · NCT06936943

• Evaluating ONO-2020 for agitation in Alzheimer's patients

  This study is testing if a new medication called ONO-2020 can help reduce agitation in people with Alzheimer's disease.

  Recruiting at 36 sites Phase 2 Ono Pharmaceutical Co., Ltd. · Aichi and 38 other locations · NCT06803823

• Treatment of rhabdoid tumors with ONO-4538

  This study is testing a new treatment called ONO-4538 for people with advanced or recurring rhabdoid tumors who haven't had success with regular chemotherapy.

  Recruiting at 13 sites Phase 2 Ono Pharmaceutical Co., Ltd. · Nagoya, Aichi-ken and 13 other locations · NCT06622941

• Evaluating the safety of cenobamate for Japanese patients with partial seizures

  This study is testing how safe cenobamate is for Japanese patients with partial seizures who have already taken part in a related study.

  Recruiting at 29 sites Phase 2 Ono Pharmaceutical Co., Ltd. · Ehime and 28 other locations · NCT06590896

• Investigating ONO-2017 for Japanese patients with generalized tonic-clonic seizures

  This study is testing a new medication called ONO-2017 to see if it can help Japanese adults with generalized tonic-clonic seizures when used alongside their current epilepsy treatments.

  Recruiting at 25 sites Phase 3 Ono Pharmaceutical Co., Ltd. · Aichi and 24 other locations · NCT06579573

• Long-term safety evaluation of ONO-4538 in cancer patients

  This study is testing the long-term safety of the cancer treatment ONO-4538 in patients with different tumors who are already receiving this medication.

  Recruiting at 30 sites Phase 2 Ono Pharmaceutical Co., Ltd. · Chiba, Chiba and 43 other locations · NCT04566380

Quick answers

How many clinical trials run by Ono Pharmaceutical Co., Ltd. are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 15 countries. The most sites are in Japan (13 trials), United States (4 trials), France (3 trials), Taiwan (2 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 3: 4, Phase 1: 4, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →