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Clinical trials and research at Istituto Giannina Gaslini

• 23Clinical trials
• 19New in 30 days
• 17Countries

Newest trials

All recruiting trials (23)

• Italian Registry of Pediatric Dialysis: collecting data from kids on kidney replacement therapy

  This registry in Italy tests how collecting epidemiological, clinical, and treatment data from children on dialysis or pre-emptive kidney transplants can help centers share protocols and improve care.

  Recruiting at 12 sites Istituto Giannina Gaslini · Ancona and 11 other locations · NCT07918066

• Multi-biomarkers in DEE: a big look at genetic epilepsies

  This study tests a panel of multi-omic biomarkers in people with genetically confirmed Developmental and Epileptic Encephalopathy to help understand prognosis and potential biomarkers for future therapies.

  Recruiting at 14 sites Istituto Giannina Gaslini · Antwerp and 13 other locations · NCT07909382

• Understanding brain development in congenital hypothyroidism: comparing affected children, healthy controls, and mild thyroid conditions

  This study tests how brain development in children with congenital hypothyroidism compares to similar children without the condition and to kids with a mild thyroid finding.

  Recruiting at 3 sites Istituto Giannina Gaslini · Genova and 2 other locations · NCT07893522

• Bone health in adults with Duchenne muscular dystrophy: osteoporosis, fractures, and treatment

  This study looks at how common bone problems and fractures are in adults with Duchenne muscular dystrophy and what factors from childhood might affect bone health later on.

  Recruiting at 15 sites Istituto Giannina Gaslini · Bologna and 14 other locations · NCT07890883

• Seeing if CFTR functioncan be restored in CF through patient cells with rare mutations

  This study tests whether testing a patient’s own nasal cells in the lab can predict if CFTR-modulator therapies might help people with uncommon CF mutations.

  Recruiting at 3 sites Istituto Giannina Gaslini · Catania and 2 other locations · NCT07889973

• Gene editing and iPS cells to study and treat monogenic autoinflammatory diseases

  Researchers are testing whether correcting disease-causing mutations in patient-derived cells can help treat autoinflammatory conditions like SAVI and COPA using gene editing and iPSC technology.

  Recruiting at 2 sites Istituto Giannina Gaslini · Bari and 1 other locations · NCT07889947

• Leopard: using multi-omics to boost genetic diagnosis for neurodevelopmental disorders

  This study tests a multi-omics approach to find genetic explanations for neurodevelopmental disorders in people with moderate-to-severe intellectual disability.

  Recruiting Istituto Giannina Gaslini · Genova · NCT07884227

• Biomarker search in SMA using advanced multi-omics

  Researchers are trying to see if new biomarkers can help diagnose and monitor spinal muscular atrophy in patients and newborns.

  Recruiting at 3 sites Istituto Giannina Gaslini · Genova and 2 other locations · NCT07883655

• Predicting the course of early-onset juvenile idiopathic arthritis using a multidimensional model

  Researchers are testing a comprehensive model to predict how early-onset JIA will progress in affected children and how a small control group with iridocyclitis compares.

  Recruiting at 2 sites Istituto Giannina Gaslini · Genova and 1 other locations · NCT07882667

• AI tools to read brain MRIs in epilepsy

  Researchers are testing AI programs to help doctors read brain MRI scans in people with epilepsy to see if they can speed up diagnosis and help plan treatments.

  Recruiting at 23 sites Istituto Giannina Gaslini · Oakland, California and 22 other locations · NCT07881185

• Neuroblastoma patients' genomic and biological profile study

  This multicenter, prospective study tests profiles from blood, tumor tissue, and bone marrow to understand neuroblastoma in diagnosed, relapsed, or refractory patients.

  Recruiting at 35 sites Istituto Giannina Gaslini · Ancona and 34 other locations · NCT07881172

• National Registry for Noonan Syndrome (Italy)

  This registry will collect genetic and clinical information from people with Noonan syndrome in Italy to understand how the condition changes over time and how treatments like growth hormone may work.

  Recruiting at 35 sites Istituto Giannina Gaslini · Ancona and 34 other locations · NCT07881159

• Neuroradiology Features in Noonan Syndrome and Gene-Linked Brain Differences

  This study tests brain MRI and MR angiography in people with Noonan syndrome to see how brain imaging patterns relate to their specific genetic mutations.

  Recruiting at 10 sites Istituto Giannina Gaslini · Bari and 9 other locations · NCT07881081

• Genetic Basis of MIS-C in Children linked to COVID-19

  This study tests whether genetic factors contribute to MIS-C in children who have had COVID-19.

  Recruiting at 3 sites Istituto Giannina Gaslini · Bergamo and 2 other locations · NCT07881068

• Respiratory progression in adults with Duchenne muscular dystrophy: a long-term observational study

  This study tests how respiratory function changes over three years in adults with genetically confirmed Duchenne muscular dystrophy.

  Recruiting at 13 sites Istituto Giannina Gaslini · Bologna and 12 other locations · NCT07879989

• Alexithymia and emotional dysregulation in children with epilepsy

  This study tests how alexithymia and emotional regulation relate to epilepsy in kids aged 10–18 and compares them with healthy peers.

  Recruiting at 2 sites Istituto Giannina Gaslini · Alessandria and 1 other locations · NCT07879976

• Understanding congenital bone marrow failure and related disorders through a national network

  This project tests whether people with rare inherited bone marrow failure syndromes or related conditions really have the underlying genetic causes, by collecting data and samples across multiple centers.

  Recruiting at 4 sites Istituto Giannina Gaslini · Avellino and 3 other locations · NCT07877727

• Newborn screening for AADC deficiency in Liguria

  This project tests a newborn screening approach for AADC deficiency in Liguria to see if many newborns can be identified early and referred for care.

  Recruiting at 10 sites Istituto Giannina Gaslini · Genova and 9 other locations · NCT07877714

• DNA sequencing of patient and family samples to help diagnose rare genetic diseases

  We’re testing whether whole-exome or whole-genome sequencing of patients and their parents can help diagnose rare genetic diseases when other findings are not yet clear.

  Recruiting Istituto Giannina Gaslini · Genova · NCT07877688

• How the CF medicines elexacaftor, tezacaftor, and ivacaftor behave in the body

  This study tests how the CF medicines elexacaftor, tezacaftor, and ivacaftor move through the body in patients with cystic fibrosis who are already taking the combination therapy.

  Recruiting Phase 4 Istituto Giannina Gaslini · Genova · NCT07809867

• Pediatric Skull Fracture Detection with Ultrasound in the Emergency Department

  This study tests whether point-of-care skull ultrasound can accurately detect skull fractures in children with minor head injuries compared with CT scans.

  Recruiting Istituto Giannina Gaslini · Genova, Italy · NCT07636902

• Sucrosomial iron for children with celiac disease and iron deficiency

  This trial tests whether adding oral Sucrosomial® (Sideral forte®) iron drops to a gluten-free diet helps children aged 8–18 with newly diagnosed celiac disease and low iron or anemia recover hemoglobin and iron stores faster than diet alone.

  Recruiting Istituto Giannina Gaslini · Genova, Italy · NCT07563582

• ADRIS 2.1 driving simulator for adolescents with ADHD.

  This project will test whether the ADRIS 2.1 driving simulator can measure and train driving-related skills in adolescents aged 13–18 with ADHD.

  Recruiting at 2 sites Istituto Giannina Gaslini · Genoa, GE and 1 other locations · NCT07478458

Quick answers

How many clinical trials run by Istituto Giannina Gaslini are recruiting right now?

23, as of November 12, 2026. 19 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 17 countries. The most sites are in Italy (23 trials), Belgium (2 trials), Germany (2 trials), Spain (2 trials), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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