Sponsor or institution

Clinical trials and research at Children's Hospital of Orange County

• 6Clinical trials
• 5NIH research projects
• 1Country

Newest trials

All recruiting trials (6)

• Acupuncture for pediatric disorders of gut–brain interaction

  This trial will test whether acupuncture can reduce symptoms in children and teens (ages 8–17) with disorders of gut–brain interaction.

  Recruiting Children's Hospital of Orange County · Irvine, California · NCT07435610

• Heart and blood vessel changes in mucopolysaccharidosis (MPS)

  This project will see if people with mucopolysaccharidosis (MPS) have faster artery thickening or stiffening and different blood or urine markers linked to heart and vessel problems than people without MPS.

  Recruiting at 2 sites Children's Hospital of Orange County · Orange, California and 2 other locations · NCT07361536

• Using Suramin to Treat Autism in Boys Aged 5-14

  This study is testing if a drug called suramin can help boys aged 5 to 14 with autism feel better.

  Recruiting at 2 sites Phase 2 Children's Hospital of Orange County · Orange, California and 1 other locations · NCT06866275

• Analyzing patient preferences for cryotherapy tubing placement

  This study is trying to see if patients prefer cryotherapy tubing placed towards their head or feet during recovery from knee surgery and how it affects their comfort and pain levels.

  Recruiting Children's Hospital of Orange County · Orange, California · NCT06772662

• Testing a device for pain relief in children with post-concussion syndrome and COVID symptoms

  This study is testing a device that uses tiny needles on the ear to see if it can help children with post-concussion syndrome and COVID symptoms feel better.

  Recruiting Children's Hospital of Orange County · Orange, California · NCT04978571

• Treatment for infantile spasms using fenfluramine

  This study is testing if a medication called fenfluramine can help young children with hard-to-treat infantile spasms feel better and have fewer seizures.

  Recruiting Phase 2 Children's Hospital of Orange County · Los Angeles, California and 1 other locations · NCT04289467

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Long-term brain imaging and thinking skills in people born very premature

  A long-term study follows people born very preterm to see how their brain structure and thinking skills change from birth through early adulthood.

  NIH research Children's Hospital of Orange County · Orange, United States · NIH-11378747

• Cardiovascular health in children with MPS I and IVA

  This grant studies how heart and blood vessel problems develop in kids with MPS I and IVA, and how to monitor and improve their cardiovascular health.

  NIH research Children's Hospital of Orange County · Orange, United States · NIH-11372893

• Combined AAV gene therapy for dogs with MPS I

  Researchers are giving a combination AAV-based gene therapy to dogs with MPS I to try to restore the missing IDUA enzyme throughout the body and brain.

  NIH research Children's Hospital of Orange County · Orange, United States · NIH-11289354

• Gene therapy to treat a genetic disorder in dogs

  This study is testing a new gene therapy to help dogs with Canine Mucopolysaccharidosis Type I by delivering special genes that can fix a missing enzyme, aiming to make them feel better and live healthier lives.

  NIH research Children's Hospital of Orange County · Orange, United States · NIH-11046559

• Investigating how shunt blockages occur in hydrocephalus treatment.

  This study is looking into why shunts used to treat hydrocephalus sometimes stop working, and it's creating a special system to mimic the conditions in the body to find ways to make these shunts better, which could help patients have more successful treatments.

  NIH research Children's Hospital of Orange County · Orange, United States · NIH-10795920

Quick answers

How many clinical trials run by Children's Hospital of Orange County are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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