WormBase: a life science data hub for C. elegans and other nematodes
Official title: WormBase: a core data resource for C. elegans and other nematodes
Funded at California Institute of Technology · NIH-11419596 · Data updated 2026-11-12
Aimed at continuously improving WormBase, a key online data resource used by researchers studying C. elegans and related nematodes, to help scientists access genome and gene information more efficiently.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California Institute of Technology NIH-funded |
| Lab location | 1 site (Pasadena, United States) |
| Project start | July 20, 2000 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,296,173 |
| NIH project number | 5U24HG002223-27 |
| Project ID | NIH-11419596 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable to patients directly; focused on scientists and researchers using nematode data.
✕Less likely to help
Patients cannot participate directly in this infrastructure grant.
What this research studies
This grant supports expanding and updating WormBase, a widely used knowledgebase that catalogs the C. elegans genome, gene functions, interactions, and related data. The project will migrate to Alliance of Genome Resources infrastructure for better data ingest, storage, and access through downloads, API, and web portal. It also focuses on improving curation pipelines, ontology standards, and the display of nematode data to keep pace with growing publications and datasets. The effort benefits researchers who rely on accurate, up-to-date reference information to design experiments and interpret results.
Why it matters
Potential benefit: If successful, researchers will have faster, more reliable access to nematode genetics data, accelerating discoveries that could translate to broader biological understanding and potential medical insights.
How similar studies have gone: Other large-scale organism/genome knowledgebases have successfully scaled with automated curation and data integration efforts; this project continues that trajectory for nematodes.
Where this research is happening
-
California Institute of Technology
Pasadena, United States Active
Researchers
- Principal investigator: Sternberg, Paul Warren — California Institute of Technology
- Study coordinator: Sternberg, Paul Warren
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.