NIH-funded research U01 cooperative agreement

West Africa self-sampling HPV program for women living with HIV/AIDS

Official title: West Africa Self-Sampling HPV Based Cervical Cancer Control Program (WA-SS-HCCP) for WLWHA: Barriers, challenges, and needs

Funded at Northwestern University · NIH-11535391 · Data updated 2026-11-12

A U01 grant to test a self-sampling HPV screening approach for women living with HIV/AIDS in West Africa to help catch cervical cancer earlier.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionNorthwestern University
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 7, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$110,191
NIH project number3U01CA275129-05S1
Project IDNIH-11535391 on NIH RePORTER

Who could benefit from this research

Could help

Women living with HIV/AIDS in West Africa who have access to partner clinics and CHWs and are eligible for HPV screening.

Less likely to help

WLWHA who cannot access self-sampling kits or follow-up care in the network may not benefit from this model.

What this research studies

This project partners with clinics in Mali and Nigeria to offer self-collected HPV tests to WLWHA, using trained community health workers to educate, collect samples, remind patients about follow-up, and assist with referrals. It aims to create a practical, “detect-to-treat” workflow that leverages HIV care networks to reach high-risk women who often lack access to cervical cancer screening. The study will adapt existing programs to the West African setting, evaluate how well the self-sampling and referral system works, and identify barriers and needs to sustain the approach. By focusing on WLWHA, the project seeks to reduce cervical cancer mortality in a group with elevated risk and to inform scalable screening models for LMICs and underserved populations in the US as applicable.

Why it matters

Potential benefit: If successful, this approach could increase early detection and treatment of cervical cancer among WLWHA, potentially reducing cancer-related morbidity and mortality.

How similar studies have gone: Previous work supports self-sampling as a feasible screening option; this project extends it to WLWHA in LMIC settings to test a practical implementation.

Where this research is happening

  • Northwestern University
    Chicago, United States
    Active

Researchers

  • Principal investigator: Hou, Lifang — Northwestern University
  • Study coordinator: Hou, Lifang

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.