NIH-funded research NIH-funded research

Improving mental health and medication adherence for men who have sex with men in South Africa

Official title: Addressing mental health and medication adherence among MSM in South Africa

Funded at Emory University · NIH-10925541 · Data updated 2026-11-12

This study is testing a new program to help men who have sex with men in South Africa improve their mental health and stick to their HIV medications, so they can feel better and stay healthy.

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Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionEmory University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startAugust 19, 2024
Project endJuly 31, 2027
Funding year2024
Award (this year)$198,531
NIH project number1R34MH135806-01A1
Project IDNIH-10925541 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are men who have sex with men living in South Africa who are at risk for HIV and may be experiencing mental health challenges.

Less likely to help

Patients who do not identify as men who have sex with men or those who are not at risk for HIV may not benefit from this research.

What this research studies

This research aims to develop and pilot an integrated intervention that focuses on improving mental health and medication adherence among men who have sex with men (MSM) in South Africa, a group facing high rates of HIV. The project will address the interconnected issues of mental health, such as depression, and the adherence to HIV prevention and treatment medications. By utilizing evidence-based approaches like problem-solving therapy and minority stress theory, the intervention seeks to provide tailored support to enhance both mental well-being and medication adherence. Participants will engage in programs designed specifically for their needs, aiming to improve health outcomes in this vulnerable population.

Why it matters

Potential benefit: If successful, this research could lead to improved mental health and better adherence to HIV medications for MSM, ultimately reducing HIV transmission rates.

How similar studies have gone: There is emerging evidence that integrated mental health and medication adherence interventions can be effective, although this specific approach targeting MSM is relatively novel.

Where this research is happening

  • Emory University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Operario, Don — Emory University
  • Study coordinator: Operario, Don

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.