WARRIORS: Should women with small abdominal aortic aneurysms get early repair or stay under surveillance?
Official title: 1/2 Women's Aneurysm Research: Repair Immediately Or Routine Surveillance: WARRIORS trial
Funded at Stanford University · NIH-11599311 · Data updated 2026-11-12
A large international study is testing whether women with small abdominal aortic aneurysms should have early repair or watchful waiting, to see if earlier treatment improves survival and quality of life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | September 5, 2025 |
| Project end | August 31, 2032 |
| Funding year | 2026 |
| Award (this year) | $1,355,824 |
| NIH project number | 4UH3HL181184-02 |
| Project ID | NIH-11599311 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women aged 50+ with small, asymptomatic AAAs (4.0–5.4 cm) eligible for EVAR.
✕Less likely to help
Women outside the 50+ age range or with aneurysms not suitable for EVAR may not benefit.
What this research studies
This trial focuses on women 50 and older with small, asymptomatic abdominal aortic aneurysms and compares early endovascular repair to routine surveillance. It uses random assignment to groups, with data gathered from registries and electronic health records to track outcomes over five years. The study aims to understand whether earlier intervention reduces AAA-related death and rupture, while also weighing costs and quality of life. Patients may benefit from clearer guidance on when to treat and how to minimize risks.
Why it matters
Potential benefit: If successful, the trial could provide clearer guidelines to improve survival and quality of life for women with small AAAs.
How similar studies have gone: Previous studies have focused on men; this trial addresses a critical gap in understanding sex-specific AAA management.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Arya, Shipra — Stanford University
- Study coordinator: Arya, Shipra
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.