Voltage dynamics in brain circuits for guiding vision and movement
Official title: Voltage dynamics of local and long-range circuits in visuomotor integration
Funded at University of Minnesota · NIH-11609394 · Data updated 2026-11-12
This NIH grant supports research to understand how the brain predicts visual input during movement by studying specific brain circuits in mice and people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | September 15, 2026 |
| Project end | September 14, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,159,362 |
| NIH project number | 1R56EY038275-01A1 |
| Project ID | NIH-11609394 on NIH RePORTER |
Who could benefit from this research
✓Could help
Anyone with a condition affecting visuomotor processing or visual cortex could benefit from insights, but this project uses animal models and may inform future human studies.
✕Less likely to help
Direct patient benefit is not immediate; the work is mechanistic and in animals with potential long-term implications for human vision disorders.
What this research studies
Researchers will use very fast voltage imaging to see how certain neurons in the visual cortex respond when vision and movement don’t match, such as when you move in a virtual world. They will test if these responses depend on active movement, and whether they come from a balance between long-range motor signals and local visual signals. The study combines cutting-edge imaging with genetic tools to isolate neuron groups involved in predicting visual flow during locomotion. Findings could clarify how the brain detects and corrects mismatches between what we see and what we expect to see while moving.
Why it matters
Potential benefit: A clearer picture of how visuomotor prediction works could inform treatments for disorders affecting perception and motor planning.
How similar studies have gone: Prior work shows that visuomotor prediction involves specific interneurons and circuits, supporting feasibility of this approach.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Kannan, Madhuvanthi — University of Minnesota
- Study coordinator: Kannan, Madhuvanthi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.