NIH-funded research NIH-funded research

Using new linked databases to cut postoperative opioid use after inpatient surgery

Official title: The Use of Novel Linked Databasesto Reduce Postoperative Opioid Use Among Patients Undergoing Inpatient Surgery

Funded at Stanford University · NIH-11415076 · Data updated 2026-11-12

A study using linked patient data from hospital records to understand and reduce long-term opioid use after surgery, especially in older adults.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startSeptember 1, 2023
Project endJuly 31, 2028
Funding year2026
Award (this year)$658,667
NIH project number5R33DA059168-03
Project IDNIH-11415076 on NIH RePORTER

Who could benefit from this research

Could help

Older adults undergoing inpatient surgery, whose perioperative care data and long-term opioid outcomes can be analyzed.

Less likely to help

Patients not represented in the linked datasets or without long-term follow-up data may not benefit.

What this research studies

This project will connect large hospital data sets to track how different perioperative care practices affect long-term opioid use after inpatient surgery. Researchers will analyze how intraoperative opioid exposure and other perioperative factors relate to persistent opioid use and potential opioid use disorder. The goal is to identify effective strategies to minimize long-term opioid problems for older adults undergoing surgery. The work relies on real patient data from multiple centers and will inform future clinical decisions and guidelines.

Why it matters

Potential benefit: If successful, the findings could guide perioperative care to reduce long-term opioid problems after surgery, improving safety and outcomes for patients.

How similar studies have gone: Prior work with linked perioperative datasets has shown promise in identifying factors associated with PPOU, though data limitations remain a challenge.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Sun, Eric — Stanford University
  • Study coordinator: Sun, Eric

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.