NIH-funded research R21 grant

Using machine learning to reduce unnecessary lab tests in pediatric intensive care.

Official title: ML-ROVER: Machine Learning to Reduce Laboratory Test Overutilization

Funded at University of Rochester · NIH-10948765 · Data updated 2026-11-12

This study is working to help doctors in pediatric intensive care units know when lab tests are really needed for kids, using smart computer tools to make sure tests are only done when they can truly help, which will lead to better care and fewer complications.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startAugust 1, 2024
Project endJuly 31, 2026
Funding year2024
Award (this year)$172,785
NIH project number1R21HS030123-01
Project IDNIH-10948765 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are pediatric patients in intensive care units who are at risk of undergoing unnecessary laboratory tests.

Less likely to help

Patients who are not in intensive care or do not require laboratory testing will likely not benefit from this research.

What this research studies

This research aims to tackle the issue of unnecessary laboratory tests in pediatric intensive care units, which can lead to complications like iatrogenic anemia. By utilizing machine learning techniques, the project seeks to develop predictive models that can identify when lab tests are truly needed, thereby improving patient care. The study will leverage existing electronic health records and clinical databases to create a more effective clinical decision support system tailored for pediatric patients. The goal is to ensure that lab tests are only performed when medically necessary, enhancing the overall quality of care.

Why it matters

Potential benefit: If successful, this research could significantly reduce the number of unnecessary lab tests, leading to better patient outcomes and reduced complications for children in intensive care.

How similar studies have gone: While there have been few predictive models for adults, this approach is novel in the pediatric context and has not been extensively tested.

Where this research is happening

  • University of Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Dziorny, Adam C. — University of Rochester
  • Study coordinator: Dziorny, Adam C.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.