NIH-funded research NIH-funded research

Using light to control chemical reactions for creating complex molecules

Official title: Photothermal Catalysis: Using light to thermally generate reactive intermediates with temporal and spatial control

Funded at Princeton University · NIH-10915530 · Data updated 2026-11-12

This study is exploring how we can use light to help create complex molecules more efficiently, which could be really helpful for making new medicines and improving chemical processes.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPrinceton University
NIH-funded
Lab location1 site (Princeton, UNITED STATES)
Project startSeptember 1, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$410,000
NIH project number5R35GM150839-02
Project IDNIH-10915530 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for benefiting from this research include individuals involved in pharmaceutical development or those requiring advanced chemical synthesis techniques.

Less likely to help

Patients who are not involved in the pharmaceutical or chemical industries may not receive direct benefits from this research.

What this research studies

This research investigates how light can be used to precisely control chemical reactions that form complex molecules. By utilizing photocatalysis, the project aims to achieve high-temperature reactions with spatial and temporal precision, allowing for the selective generation of reactive intermediates. The approach involves using specific nanoparticles or dyes that, when exposed to visible light, create localized heating, enhancing the efficiency of chemical processes. This innovative method could lead to advancements in organic synthesis and pharmaceutical development.

Why it matters

Potential benefit: If successful, this research could significantly improve the efficiency and precision of drug development and chemical manufacturing.

How similar studies have gone: Other research has shown success with photocatalysis and similar approaches, indicating a promising avenue for further exploration.

Where this research is happening

  • Princeton University
    Princeton, United States
    Active

Researchers

  • Principal investigator: Stache, Erin — Princeton University
  • Study coordinator: Stache, Erin

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.