UroMarker urine test to screen obstructive sleep apnea in children
Official title: UroMarker Test Panel for Obstructive Sleep Apnea
Funded at Pgxl Technologies, LLC · NIH-11393085 · Data updated 2026-11-12
A non-invasive urine test in kids aims to screen for obstructive sleep apnea so doctors can detect and monitor the condition more easily.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pgxl Technologies, LLC NIH-funded |
| Lab location | 1 site (Louisville, United States) |
| Project start | September 20, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $957,571 |
| NIH project number | 5R44HL174221-03 |
| Project ID | NIH-11393085 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are children affected by suspected obstructive sleep apnea who would benefit from a non-invasive screening method.
✕Less likely to help
Children without sleep-related breathing issues or those who already have a confirmed diagnosis and comprehensive management plan may see limited additional benefit.
What this research studies
This project develops a urine-based multiplex immunoassay that could screen children for obstructive sleep apnea without overnight sleep studies. It targets pediatric patients and seeks to improve screening, diagnosis, and monitoring as treatment progresses. By comparing urine biomarkers with current standards, the study aims to provide a faster, child-friendly option that may reduce the need for polysomnography. The work is designed to fit into pediatric care pathways and could be used in clinics and potentially at home under supervision.
Why it matters
Potential benefit: If successful, children could be screened more quickly and comfortably, leading to earlier diagnosis and better management of OSA.
How similar studies have gone: Prior approaches show promise for biomarker-based screening, but there is a need for validated pediatric urine-based tests for OSA.
Where this research is happening
-
Pgxl Technologies, LLC
Louisville, United States Active
Researchers
- Principal investigator: Burns, Christopher Thomas — Pgxl Technologies, LLC
- Study coordinator: Burns, Christopher Thomas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.