Understanding ventricular tachycardia burden to improve hospital care
Official title: Calculating In-patient Ventricular Tachycardia Burden and Assessing its Impact on Outcomes
Funded at University of California, San Francisco · NIH-11292793 · Data updated 2026-11-12
A study using hospital ECG data from ICU patients to create a new measure of how much ventricular tachycardia occurs and how it affects outcomes.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | July 6, 2026 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $246,000 |
| NIH project number | 1R21HL177738-01A1 |
| Project ID | NIH-11292793 on NIH RePORTER |
Who could benefit from this research
✓Could help
ICU patients with ventricular tachycardia or VT-like episodes who are represented in the UCSF VT Database and who have complete ECG and clinical data.
✕Less likely to help
Patients outside ICU settings or without VT episodes may not directly benefit from this VT burden metric.
What this research studies
Patients with serious heart rhythm problems in the hospital could benefit from clearer signals about how VT episodes relate to their care. The project will analyze a large UCSF VT database with ECG and clinical data to define a new VT burden metric. By linking VT features like duration and heart rate to interventions and outcomes, the team hopes to improve ECG monitoring and risk prediction for future patients. The research team includes hospital medicine, nursing, and cardiology experts working together to translate data into actionable hospital care improvements.
Why it matters
Potential benefit: If successful, this work could lead to better risk stratification and monitoring for ICU patients with VT, potentially guiding timely interventions.
How similar studies have gone: Previous work showed variations in VT features; this project aims to build on that by creating a new burden metric that could improve outcomes prediction.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Prasad, Priya April — University of California, San Francisco
- Study coordinator: Prasad, Priya April
Related research
Other NIH-funded projects on the same topics.
-
Map heart tissue to guide VT ablation with AI help
A patient-oriented project aims to use AI-based mapping to better identify abnormal heart tissue responsible for ventricular tachycardia and guide safer, faster ablation.
-
Proton SBRT for refractory ventricular tachycardia with real-time 3D/4D imaging
A patient-facing study exploring a proton-based, noninvasive radiation therapy to treat stubborn VT using advanced 3D and 4D imaging to target the heart safely.
-
Venous ethanol ablation to treat ischemic VT (VE-VT)
A new treatment approach uses ethanol delivered through heart veins to help stop dangerous heart rhythms in patients with previous heart damage.
-
Novel gene therapy tools to prevent dangerous heart rhythms
A small grant supports testing gene-therapy methods to stop ventricular tachycardia after a heart attack, with the goal of helping people at risk of sudden heart rhythm problems.
-
Radiation-guided ablation for ventricular tachycardia
This project tests a noninvasive radiation approach to ablate heart tissue in people with dangerous ventricular tachycardia to reduce the need for invasive procedures.
-
Low-Field MRI–Guided Robotic Catheter System for VT Ablation
A research project is testing a new low-field MRI–guided robotic catheter to improve treatment of ventricular tachycardia for patients with abnormal heart structure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.