Understanding kidney function and transport processes
Official title: Physiology Core
Funded at University of Pittsburgh at Pittsburgh · NIH-10914935 · Data updated 2026-11-12
This study is looking at how the kidneys work, especially how they move important substances around, to help us understand both healthy kidneys and those that are not working well.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $273,156 |
| NIH project number | 5U54DK137329-02 |
| Project ID | NIH-10914935 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with kidney disorders or those at risk for kidney-related health issues.
✕Less likely to help
Patients with non-kidney related health conditions are unlikely to benefit from this research.
What this research studies
This research focuses on the fundamental processes that regulate kidney function, particularly how substances are transported within the nephron, the functional unit of the kidney. It employs advanced technologies to study specific nephron segments and cells, allowing researchers to isolate and analyze the behavior of transport proteins and their regulatory mechanisms. By utilizing various subcores, including single tubule analysis, electrophysiology, and live-cell imaging, the research aims to provide insights into both healthy and diseased states of kidney function.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for kidney diseases.
How similar studies have gone: Previous research has shown success in understanding kidney function through similar methodologies, indicating a strong potential for impactful findings.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Carattino, Marcelo Daniel — University of Pittsburgh at Pittsburgh
- Study coordinator: Carattino, Marcelo Daniel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.