Understanding how variations in brain structure affect mood regulation
Official title: THE ROLE OF PARACINGULATE SULCAL MORPHOLOGY IN AFFECTIVE NETWORK CONNECTIVITY
Funded at Baylor College of Medicine · NIH-11071317 · Data updated 2026-11-12
This study is looking at how certain brain structures might affect the connections that help regulate mood, with the goal of helping people understand how their unique brain features could relate to mood disorders and their treatment.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 5, 2024 |
| Project end | December 25, 2026 |
| Funding year | 2024 |
| Award (this year) | $48,974 |
| NIH project number | 1F31MH136762-01A1 |
| Project ID | NIH-11071317 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing mood disorders who have variations in their paracingulate sulcus morphology.
✕Less likely to help
Patients without mood disorders or those with no identifiable variations in their brain structure may not benefit from this research.
What this research studies
This research investigates the cingulum bundle, a key white matter fiber system that connects areas of the brain involved in mood regulation. It focuses on how variations in the paracingulate sulcus, a specific brain structure, may influence the organization of white matter and connectivity within the affective network. By using advanced imaging techniques, the study aims to uncover how these anatomical differences could affect mood disorders and their treatment. Patients may gain insights into how their unique brain structures relate to their emotional health.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for mood disorders based on individual brain anatomy.
How similar studies have gone: Previous research has shown promising results in understanding brain connectivity and its impact on mood disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Danstrom, Isabel Anastasia — Baylor College of Medicine
- Study coordinator: Danstrom, Isabel Anastasia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.