Understanding how variations in brain structure affect mood regulation

THE ROLE OF PARACINGULATE SULCAL MORPHOLOGY IN AFFECTIVE NETWORK CONNECTIVITY

NIH-funded research Baylor College of Medicine · NIH-11071317

This study is looking at how certain brain structures might affect the connections that help regulate mood, with the goal of helping people understand how their unique brain features could relate to mood disorders and their treatment.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionBaylor College of Medicine NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11071317 on NIH RePORTER

What this research studies

This research investigates the cingulum bundle, a key white matter fiber system that connects areas of the brain involved in mood regulation. It focuses on how variations in the paracingulate sulcus, a specific brain structure, may influence the organization of white matter and connectivity within the affective network. By using advanced imaging techniques, the study aims to uncover how these anatomical differences could affect mood disorders and their treatment. Patients may gain insights into how their unique brain structures relate to their emotional health.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing mood disorders who have variations in their paracingulate sulcus morphology.

Not a fit: Patients without mood disorders or those with no identifiable variations in their brain structure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for mood disorders based on individual brain anatomy.

How similar studies have performed: Previous research has shown promising results in understanding brain connectivity and its impact on mood disorders, suggesting that this approach could yield valuable insights.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Affective Disorders
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.