Understanding how the frontal cortex affects self-control

Role of Frontal Cortex in Self-Control

NIH-funded research Johns Hopkins University · NIH-11136519

This study is looking at how a part of the brain called the frontal cortex helps with self-control and managing our actions, and it’s designed for anyone interested in understanding how we can better control our thoughts and behaviors.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11136519 on NIH RePORTER

What this research studies

This research investigates the role of the frontal cortex in self-control and behavioral control, which are essential for managing actions, thoughts, and desires. By using neuroimaging and behavioral tasks, the study aims to uncover the neuronal mechanisms that contribute to response inhibition and self-control. The research will involve training monkeys to perform tasks that differentiate between motor control and self-control, helping to clarify whether these processes share the same brain circuits or operate independently.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals with ADHD or other behavioral control disorders.

Not a fit: Patients who do not have issues with behavioral control or self-regulation may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment options for conditions like ADHD and other disorders related to behavioral control.

How similar studies have performed: Previous research has shown promising results in understanding the brain mechanisms of self-control, suggesting that this approach could yield valuable insights.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Attention deficit hyperactivity disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.