NIH-funded research R01 grant

Understanding how the brain plans actions

Official title: Neural basis of planning

Funded at Johns Hopkins University · NIH-11105888 · Data updated 2026-11-12

This study looks at how our brains plan and choose actions by watching what happens in the brain while people play a game where they try to line up four stones before their opponent does, helping us understand how we make decisions and plan ahead.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startJune 5, 2024
Project endJanuary 31, 2029
Funding year2025
Award (this year)$665,306
NIH project number5R01MH137210-02
Project IDNIH-11105888 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation would include individuals with cognitive challenges or those interested in understanding decision-making processes.

Less likely to help

Patients with severe neurological disorders that prevent participation in cognitive tasks may not benefit from this research.

What this research studies

This research investigates the neural mechanisms involved in planning by examining how the brain selects sequences of actions from numerous alternatives. Using advanced techniques to monitor neuron activity in various brain regions, the study focuses on a task where participants aim to place four stones in a row before their opponent. This task serves as a model for understanding complex planning and decision-making processes. By analyzing the brain's activity during this task, researchers hope to uncover how cognitive functions like planning are supported by neural computations.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding of cognitive processes, potentially informing treatments for cognitive impairments.

How similar studies have gone: Previous research has shown success in understanding cognitive processes through similar experimental tasks, indicating a promising avenue for this investigation.

Where this research is happening

  • Johns Hopkins University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Lee, Daeyeol — Johns Hopkins University
  • Study coordinator: Lee, Daeyeol

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.