Understanding how the brain organizes decision-making activity
Official title: P1: Sources and Mechanisms of Sequential Activity
Funded at Princeton University · NIH-10900681 · Data updated 2026-11-12
This study looks at how the brain of a mouse makes decisions by tracking its activity during different tasks, like finding its way around or responding to sights, to better understand how certain brain areas help time those decisions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Princeton University NIH-funded |
| Lab location | 1 site (Princeton, UNITED STATES) |
| Project start | August 8, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $304,589 |
| NIH project number | 5U19NS132720-02 |
| Project ID | NIH-10900681 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with neurological conditions that impact decision-making or cognitive processes.
✕Less likely to help
Patients without neurological conditions or those not experiencing cognitive impairments may not benefit from this research.
What this research studies
This research investigates how sequential activity in the mouse brain influences decision-making processes. By examining how different tasks and conditions affect this activity, researchers aim to identify the underlying mechanisms that contribute to how decisions are made. The study involves recording neural activity during various tasks, including navigation and visual stimulation, to determine how these factors shape brain responses. Additionally, the research will explore the role of specific brain regions, such as the striatum, in controlling the timing of decisions.
Why it matters
Potential benefit: If successful, this research could lead to new insights into the neural mechanisms of decision-making, potentially informing treatments for conditions that affect cognitive function.
How similar studies have gone: Previous research has shown success in understanding brain activity related to decision-making, but this specific approach is novel and aims to uncover new mechanisms.
Where this research is happening
-
Princeton University
Princeton, United States Active
Researchers
- Principal investigator: Tank, David W — Princeton University
- Study coordinator: Tank, David W
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.